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Side 1 fra 34 resultater
Salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines
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FIELD OF THE INVENTION
The present invention relates to salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines, to a process for producing them, to their use for producing pharmaceutical compositions and to pharmaceutical compositions containing these compounds.
BACKGROUND OF THE
Salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines
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FIELD OF THE INVENTION
The present invention relates to salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines, to a process for producing them, to their use for producing pharmaceutical compositions and to pharmaceutical compositions containing these compounds.
BACKGROUND OF THE
Isomaltooligosaccharides from Leuconostoc as neutraceuticals
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This invention pertains to the use of maltosyl-isomaltooligosaccharides as a dietary supplement for birds and mammals, specifically, to promote the growth of beneficial intestinal microbes, inhibit the growth of pathogenic intestinal microbes, and for therapeutic intervention in diseases such as
Isomaltooligosaccharides to inhibit avian pathogenic intestinal bacteria
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This invention pertains to the use of maltosyl-isomaltooligosaccharides as a dietary supplement for birds and mammals, specifically, to promote the growth of beneficial intestinal microbes, inhibit the growth of pathogenic intestinal microbes, and for therapeutic intervention in diseases such as
Polynucleotides that encode the calcitonin gene-related peptide receptor coponent factor (HOUNDC44)
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FIELD OF THE INVENTION
This invention relates, in part, to newly identified polynucleotides and polypeptides; variants and derivatives of the polynucleotides and polypeptides; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; agonists and antagonists
Viscous compositions containing carbon dioxide
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TECHNICAL FIELD
Thee present invention relates to a carbon dioxide-containing viscous composition which is capable of treating or ameliorating itching accompanying mucocutaneous diseases or mucocutaneous disorders such as athlete's foot, insect bite, atopic dermatitis, nummular eczema, xeroderma,
Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1
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The present invention relates to a novel therapeutic use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine or pharmacologically acceptable salts thereof for increasing the levels of IGF-1(insulin-like growth factor 1) for the therapeutic treatment or prophylaxis or cytological
Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1
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This is a 371 of PCT/IT97/00113 filed May 15, 1997.
The present invention relates to a novel therapeutic use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine or pharmacologically acceptable salts thereof for increasing the levels of IGF-1 (insulin-like growth factor 1) for the
Modulation of substance P by compounds containing calcium sulfate and methods relating thereto
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TECHNICAL FIELD
The present invention relates generally to a method of modulating substance P by compounds containing calcium sulfate, particularly syngenite, gorgeyite and gypsum, and more specifically, to the synthesis of such compounds as well as their use to treat a variety of conditions
Glycoside-hydrolase enzyme inhibitors
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BACKGROUND OF THE INVENTION
Carbohydrates are eaten either as simple sugars or as more complex molecules called polysaccharides, which are built up from simple sugar units and of which the starch of potatoes, bread, etc., is a well-known example. The body absorbs carbohydrates from the small
Glycoside-hydrolase enzyme inhibitors
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BACKGROUND OF THE INVENTION
Carbohydrates are eaten either as simple sugars or as more complex molecules called polysaccharides, which are built up from simple sugar units and of which the starch of potatoes, bread, etc., is a well-known example. The body absorbs carbohydrates from the small
Amylase inhibitor
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BACKGROUND OF THE INVENTION
It is known that in animals and man, after the intake of starchy foodstuffs and beverages, hyperglycaemias arise which are caused by a rapid splitting of the starch by amylases of the digestive tract according to the following equation:
These hyperglycaemias are
Deuterium-enriched pyridinonecarboxamides and derivatives
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SUMMARY OF THE INVENTION
The present invention is concerned with deuterium-enriched pyridinone carboxamides and derivatives thereof of formula I,
##STR00002##
Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),
Deuterium-enriched pyridinonecarboxamides and derivatives
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SUMMARY OF THE INVENTION
The present invention is concerned with deuterium-enriched pyridinonecarboxamides and derivatives thereof of formula 1,
##STR00002## Wherein, R.sub.1 and R.sub.2 are independently, H, D (deuterium with enrichment of 1%-100%), F, Cl, CD.sub.3 (methyl-d.sub.3),
Tachykinin (NK.sub.2) antagonists
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BACKGROUND OF THE INVENTION
Over the last decade, major advances have been made in the understanding of the biology of the mammalian tachykinin neuropeptides. It is now well established that substance-P, neurokinin A (NKA), and neurokinin B (NKB), all of which share a common C-terminal sequence
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