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14 resultater
Method for diagnosing non-healing ulcers
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Chronic, non-healing cutaneous ulcers (hereinafter referred to as "ulcers") are a major unresolved health problem. Typically, cutaneous ulcers appear on an extremity, and are often indicative of a secondary disorder, i.e., a peripheral circulatory disorder. Cutaneous ulcers which are secondary to a
Use of protease inhibitors for treating skin wounds
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BACKGROUND OF THE INVENTION
The skin acts as the body's first line of defense against infection. Accordingly, it is important that lesions or wounds in the skin must be rapidly closed to prevent infection. Some types of wounds, however, are resistant to healing under normal physiological conditions.
Serine protease inhibitors-N-substituted derivatives
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Serine protease inhibitors-keto and di-keto containing ring systems
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which include elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Val-pro containing .alpha.-keto oxadiazoles as serine protease inhibitors
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BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in common a catalytic triad consisting of Serine-195, Histidine-57 and Aspartic acid-102 (chymotrypsin numbering system). Human
Indole and tetrahydroisoquinoline containing Alpha-keto oxadiazoles as serine protease inhibitors
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The present invention relates to certain substituted oxadiazole nonpeptides, which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in
Protease inhibitors
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This invention relates to a novel microorganism and accumulated products produced therefrom. More particularly, this invention relates to a novel strain belonging to Genus Streptomyces, a process for producing various procidins by use of said strain and novel procidins obtained by said process.
The
Serine protease inhibitors-proline analogs
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The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Serine protease inhibitors
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Log ind / Tilmeld
The present invention relates to certain substituted oxadiazole nonpeptides, which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes, which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in
Serine protease inhibitor--tripeptoid analogs
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Log ind / Tilmeld
The present invention relates to certain substituted oxadiazole, thiadiazole and triazole peptoids which are useful as inhibitors of serine proteases.
BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin.
Serine protease inhibitors-cycloheptane derivatives
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BACKGROUND OF THE INVENTION
The serine proteases are a class of enzymes which includes elastase, chymotrypsin, cathepsin G, trypsin and thrombin. These proteases have in common a catalytic triad consisting of Serine-195, Histidine-57 and Aspartic acid-102 (chymotrypsin numbering system). Human
Medicament for preventing and treating pseudomonas aeruginosa infections and method of its preparation
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The present invention relates to a human .gamma.-globulin preparation used for prevention and treatment of diseases caused by infection with P. aeruginosa as well as to a process of producing the gamma globulin preparation.
P. aeruginosa has brought forward various problems in the medical field as a
Tripeptide derivatives containing pyroglutamic acid residue
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present invention relates to novel tripeptide derivatives containing a pyroglutamic acid residue and more particularly, to tripeptide derivatives containing a pyroglutamic acid residue which possess a protease inhibitory activity, or
Composition for the treatment of helicobacter pylori infection
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FIELD OF THE INVENTION
The present invention relates to a composition for the treatment of the infection by bacteria Helicobacter pylori which is one of causes for gastric ulcer, duodenal ulcer, and the like.
PRIOR ART OF THE INVENTION
It has been so far thought that peptic uclers such as gastric
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