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unsaturated fatty acid/ødem
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[Protective effect of unsaturated fatty acids in adrenaline-induced pulmonary edema and hypobaric hypoxia (biological significance of catecholamine hyperlipidemia)].
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A model for research on the blood-brain barrier disruption induced by unsaturated fatty acid emulsion.
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OBJECTIVE
The authors investigated whether fatty acid emulsion affects the blood-brain barrier (BBB), whether disrupted BBB is reversible, and whether the fatty acid emulsion technique may be a model for BBB research.
METHODS
The fat emulsion was made with 0.05 mL of oleic acid or linoleic acid and
Modulation of immunogenic keratitis in rabbits by topical administration of poly-unsaturated fatty acids.
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Several unsaturated fatty acids are precursors of prostaglandins and leukotrienes. Depending on their precursor, these prostaglandins and leukotrienes have different biological characteristics. The effects of topically administered fatty acids on an experimentally provoked inflammatory keratitis
The pathogenesis of methylhydrazine sulfate induced distal tail gangrene.
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Finely divided methylhydrazine sulfate was fed to 42 rats at a concentration of 300 mg per kg of ground commercial diet. After 42 days most of the rats developed hyperkeratosis and edema of the terminal 2-6 cm of the tail. Twenty-five rats fed longer than 98 days all developed tail tip gangrene
Dietary fat composition alters pulmonary function in pigs.
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OBJECTIVE
We investigated the effect of various dietary fats on pulmonary surfactant composition and lung function changes that occur before and after endotoxin infusion in pigs.
METHODS
Eighteen pigs were assigned to three groups (n = 6 per group) to receive a diet of protein (20% of calories),
Multiple topical applications of arachidonic acid to mouse ears induce inflammatory and proliferative changes.
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The response to daily topical applications of arachidonic acid (0.25-4 mg/ear/day) to the ears of outbred CD-1 mice was monitored. The first application produced erythema, extravasation of plasma proteins resulting in an increase in ear weight, and some neutrophil accumulation (detected
Anti-inflammatory activities and mechanisms of action of the petroleum ether fraction of Rosa multiflora Thunb. hips.
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BACKGROUND
The hip of Rosa multiflora Thunb. has been traditionally used as a dietary supplement and a herbal remedy for the treatment of various diseases including cold, flu, inflammation, osteoarthritis, rheumatoid arthritis and chronic pain in China.
OBJECTIVE
To explore the anti-inflammatory
Antagonists and inhibitors of lipid mediators in experimental inflammation of the cornea.
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In experimental immunogenic keratitis, provoked in rabbits by intracorneal injection of 20 microliters of human serum albumin (HSA), various anti-inflammatory agents were studied in their effects on corneal edema, neovascularisation and leukocyte infiltration. Prophylactic treatment with a
Loss of essential membrane lipids and ascorbic acid from rat brain following cryogenic injury and protection by methylprednisolone.
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Previous work has shown that unsaturated fatty acid components of model membrane phospholipids in vitro, damaged via a free radical mechanism, are protected by the presence of cholesterol in these membranes. The participation of these membrane lipids in the pathogenesis of traumatic injury to brain
Depletion of hepatic coenzyme A derivatives is one of the markers of the toxicity of orally administered secondary autoxidation products of linoleic acid in rat.
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When 400 mg/rat/day of secondary autoxidation products of linoleic acid was orally administered 3 times to rats, they died at 30-40 h after the third dose. To search the markers of the toxicity of secondary products in vivo, the rats were killed at 24h after the third dose, and conditions of their
Cerebral microvascular changes induced by rich cholesterol and saturated fatty acid diet in Wistar rats.
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The impact of an excess of fatty acids in the diet on cardiovascular diseases has been studied and discussed both in human and animal studies. Generally, excessive saturated fats increase the risk, while unsaturated fats are considered less harmful. Our aim was to perform an experimental study in
Diet-related toxemia in pregnancy. I. Fat, fatty acids, and cholesterol.
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Toxemia in pregnancy (preeclampsia)is characteristerized by a combination of at least two of the following clinical symptoms: hypertension, edema, and proteinuria. In three successive trials over three consecutive years, the dietary intake of a selected number of young pregnant women attending a
Anti-inflammatory effects of Trigonella gharuensis: Comparative analysis in BALB/C mouse model.
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Plants are extensively used in treating inflammatory disorders. The current study focused on evaluating anti-inflammatory potential of Trigonella gharuensis. The ethanolic and n-hexane extracts of T. gharuensis were given orally at the dose of 400mg/kg/day. Various in vivo inflammatory models such
Ailanthus altissima (Miller) Swingle seed oil: chromatographic characterization by GC-FID and HS-SPME-GC-MS, physicochemical parameters, and pharmacological bioactivities.
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This study aimed to identify the physicochemical and the chemical properties of Ailanthus altissima (Miller) Swingle seed oil and to evaluate its in vitro antioxidant and antibacterial activities and in vivo analgesic and anti-inflammatory activities. The fatty acids' composition was determined
Actions of Cannabis sativa L. fixed oil and nano-emulsion on venom-induced inflammation of Bothrops moojeni snake in rats
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Background: Bothrops moojeni snake venom (VBm) has toxins that cause pronounced tissue damage and exacerbated inflammatory reaction. Cannabis sativa L. is a plant species that produces an oil (CSO) rich in unsaturated fatty acids.
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