Participants will receive fish oil gelcaps that contain 1.6 grams of omega-3 fatty acids (800 mg of EPA, 600 mg DHA, 200 mg other omega-3 fatty acids) for 12 weeks.

Participants will receive 1 gram of oleic sunflower oil for 12 weeks.

Participants will receive fish oil gelcaps that contain 1.6 grams of omega-3 fatty acids (800 mg of EPA, 600 mg DHA, 200 mg other omega-3 fatty acids) for 12 weeks.
Fish oil that contains omega-3 fatty acids: Fish oil gelcaps that contain 800 mg of EPA, 600 mg of DHA, 200 mg other omega-3 fatty acids

Fish Oil

Participants will receive 1 gram of oleic sunflower oil for 12 weeks.
Fish oil that contains omega-3 fatty acids: Fish oil gelcaps that contain 800 mg of EPA, 600 mg of DHA, 200 mg other omega-3 fatty acids

Placebo

Total

Sex: Female, Male

Region of Enrollment

Markers of immune senescence will include change in the expression of the senescence markers CD28 and CD57 on the surface of peripheral CD4+ and CD8+ T lymphocytes. We will measure the percentage of CD4+ and CD8+ T lymphocytes that are CD28-/CD57- or CD28-/CD57+. We will subtract the percentage obtained at Week 12 from the baseline percentage to calculate the change scores.

Change in Markers of Immune Senescence Between Baseline Values and Values After 12 Weeks of Supplementation

Overall Study

Barbara Swanson

HIV Infection

Fish oil gelcaps that contain 800 mg of EPA, 600 mg of DHA, 200 mg other omega-3 fatty acids

Fish oil that contains omega-3 fatty acids

Gelcaps that contain 1 gram of oleic sunflower oil

Rush University Medical Center

Fish Oil for HIV-Related Inflamm-aging and Immune Senescence

Participants were randomized to one of two arms:
Intervention arm = fish oil Control arm = placebo.

All gelcaps were overencapsulated to mask their contents

unsaturated fatty acid/diarré

Fish Oil for HIV-Related Inflamm-aging and Immune Senescence

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