Chest 1982-Jul
COPD and endobronchial polyposis associated with hypogammaglobulinemia. Are proteolytic enzymes involved?
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The present report describes a patient who had severe obstructive lung disease in association with acquired hypogammaglobulinemia. Evidence obtained by bronchoalveolar lavage is presented that suggests that his lung disease resulted from both a marked increase in elastase load and a reduction in protease inhibitor function.