[Neuroprotective effect of ferulic acid in vitro].
Schlüsselwörter
Abstrakt
OBJECTIVE
To investigate the neuroprotective effect of ferulic acid on PC12 cells injuries.
METHODS
With three models of PC12 cells injured by hypoxia, excitatory amino acids (EAA) and radical, the effect of ferulic acid on injured PC12 cells was observed by MTT assay.
RESULTS
Compared with three models, ferulic acid (1-100 micromol/L) could promote cell viability notably (P<0.05 or P<0.01).
CONCLUSIONS
Ferulic acid has notable protective effect on PC12 cells injured by hypoxia, EAA and radical.