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acromegaly/epileptischer anfall
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Seite 1 von 17 Ergebnisse
[Acromegaly with goiter, diabetes, steroid excretion disorder and convulsions; therapeutic considerations].
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Congenital retardation and central motor defect with later evolution of seizure disorder, orofacial dysplasia, and amyotrophy. A clinicopathologic report.
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Retarded mental and motor development was observed during the first year of life of a full-term female who had been delivered with difficulty. Generalized psychomotor seizures and dysplastic "acromegalic" facial changes began to develop when she was 8 years old, and generalized amyotrophy developed
Acromegaly in 14 cats.
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Acromegaly was diagnosed in 14 middle-aged to old cats of mixed breeding. Thirteen (93%) of the cats were male and one was female. The earliest clinical signs in the 14 cats included polyuria, polydipsia, polyphagia, all of which were associated with untreated diabetes mellitus. All developed severe
Impact of preoperative pasireotide therapy on invasive octreotide-resistant acromegaly.
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A 43-year-old woman with an 8-year history of diabetes, hypertension, and dyslipidemia presented with amenorrhea and convulsion. Her MRI scan revealed a 3.5-cm T2-hyperintense pituitary macroadenoma with suprasellar extension to the frontal lobe and bilateral cavernous sinus invasion. Her serum
Proton stereotactic radiosurgery in management of persistent acromegaly.
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OBJECTIVE
To evaluate the efficacy and safety of proton stereotactic radiosurgery (PSRS) for acromegaly that is refractory to surgical treatment and medication.
METHODS
From 1992 to 2003, 22 patients were treated at our institution for persistent acromegaly with use of PSRS. All patients had
Treatment of acromegaly: is there still a place for radiotherapy?
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OBJECTIVE
To evaluate efficacy and safety of radiotherapy on acromegaly treatment.
METHODS
We followed retrospectively 99 acromegalic patients for at least one year after radiotherapy (RT). RT had been performed after unsuccessful surgery in 91 patients and as primary treatment in eight. Time
Acromegaly: report of two patients with an unusual presentation.
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The presenting features of functionally active pituitary tumours depend on the specific hormone which is overproduced. Growth hormone (GH) producing tumours usually present with the clinical manifestations of acromegaly due to excessive GH secretion or symptoms resulting from mass effects of the
Pure endoscopic transsphenoidal surgery for treatment of acromegaly: results of 67 cases treated in a pituitary center.
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OBJECTIVE
Acromegaly is a chronic disease related to the excess of growth hormone (GH) and insulin-like growth factor–I secretion, usually by pituitary adenomas. Traditional treatment of acromegaly consists of surgery, drug therapy, and eventually radiotherapy. The introduction of endoscopy as an
Paradoxical GH response to TRH during status epilepticus in man.
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Information on GH in relation to epilepsy is sparse, and to our knowledge there is no information on GH levels during status epilepticus in man. We studied GH in serum in six patients during status epilepticus, and in a control group of six seizure-free patients with epilepsy, before and after
[Multiple endocrine neoplasia type 1 syndrome with three classical components and chiasm glioma: specific features of target organ lesions and a clinical observation].
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The article briefly reviews the specific features of target-organ lesions in multiple endocrine neoplasia type 1 (MEN1) syndrome and a clinical case of genetically confirmed MEN1 syndrome in a young female patient. Despite the relative rarity of this disease, timely diagnosis, treatment and
Transient MR changes and symptomatic epilepsy following gamma knife treatment of a residual GH-secreting pituitary adenoma in the cavernous sinus.
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OBJECTIVE
To report a rare side effect of gamma knife treatment of pituitary macroadenoma.
METHODS
In a forty-one-year old female patient acromegaly was diagnosed due to a growth hormone secreting pituitary macroadenoma. Following transsphenoidal surgery the patient underwent gamma knife treatment
Identification of a novel de novo nonsense mutation of the NSD1 gene in monozygotic twins discordant for Sotos syndrome.
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BACKGROUND
Sotos syndrome is a congenital overgrowth disorder characterized by facial gestalt, excessively rapid growth, acromegalic features and a non-progressive cerebral disorder with intellectual disability.
METHODS
The identical male twins showed somewhat different clinical, cognitive and
Anterior transcallosal approach to the colloid cysts of the third ventricle: case series and review of the literature.
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OBJECTIVE
To evaluate the results of the anterior transcallosal approach to the colloid cysts of the third ventricle.
METHODS
A retrospective analysis of the patients operated on between 1986 and 2003 was carried out. There were 19 patients (10 female, 9 male) with a median age of 43. The main
Simultaneous diagnosis of glioblastoma, cervical schwannoma, adrenal masses and growth hormone-secreting adenoma in a previously healthy patient.
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A constellation of newly diagnosed benign tumours and glioblastoma is an uncommon occurrence in a single individual. We present a case of a patient with a history of skin lipomas who presented with seizures and was found to have a left frontotemporal multifocal enhancing mass on MRI. Work-up for
Outcomes of proton therapy for patients with functional pituitary adenomas.
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OBJECTIVE
This study evaluated the efficacy and toxicity of proton therapy for functional pituitary adenomas (FPAs).
METHODS
We analyzed 165 patients with FPAs who were treated at a single institution with proton therapy between 1992 and 2012 and had at least 6 months of follow-up. All but 3
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