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acromegaly/kopfschmerz
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Analgesic effect of octreotide in headache associated with acromegaly is not mediated by opioid mechanisms. Case report.
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We report a patient with acromegaly who had severe, intractable headache unrelated to tumor size which dramatically resolved with the somatostatin analog octreotide. The analgesic effects of octreotide were neither related to significant inhibition of growth hormone nor influenced by naloxone. Our
[Analgesic effect of Sandostatin (SMS 201-995) in acromegaly headache].
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Somatostatin analogue (Sandostatin; SMS 201-995) is utilized as a therapy in acromegaly because of its efficiency in inhibiting GH secretion; it induces some clinical improvements, such as headache remission in acromegalic patient, which seem to be unrelated to Gh normalization. We have examined 8
Headache in acromegaly: dramatic improvement with the somatostatin analogue SMS 201-995.
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Two acromegalic patients with severe headache, persisting after pituitary adenomectomy followed by radiotherapy in one, were treated with the somatostatin analogue SMS 201-995. Both had been resistant to conventional headache therapy and experienced dramatic and rapid relief after the first
Analgesic effect of long-acting somatostatin receptor agonist pasireotide in a patient with acromegaly and intractable headaches.
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A 22-year-old woman presented with worsening vision loss and headaches. A diagnosis of acromegaly was confirmed after detection of an invasive pituitary macroadenoma and biochemical testing. Despite two attempts of surgical debulking of the tumour and administration of long-acting octreotide and
Short-lasting, unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome treated successfully with transsphenoidal resection of a growth hormone-secreting pituitary adenoma.
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Short-lasting, unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome was first described in 1978 as one of the trigeminal autonomic cephalgias. In this paper the authors present a patient with a growth hormone-secreting pituitary adenoma who experienced
Acromegaly diagnosed in a young woman presenting with headache and arthritis.
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BACKGROUND
A 38-year-old woman presented with severe headaches to her primary-care physician. The patient had been diagnosed with rheumatoid arthritis and had begun having headache 4 years previously. An MRI scan revealed an 11-12 mm pituitary tumor. Her physical examination was unremarkable for the
Cerebral arteriopathy with subcortical infarcts and leukoencephalopathy in acromegalic patient with severe headache.
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A 68-year-old female patient was admitted in our clinic with severe frontal bilateral headache, dizziness, depression and cognitive decline in the context of a previously diagnosed acromegaly. She also had high blood pressure, dyslipidemia, secondary diabetes mellitus. Acromegaly was caused by a
Truncated somatostatin receptor 5 may modulate therapy response to somatostatin analogues--Observations in two patients with acromegaly and severe headache.
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BACKGROUND
Somatotropinomas have unique "fingerprints" of somatostatin receptor (sst) expression, which are targets in treatment of acromegaly with somatostatin analogues (SSAs). However, a significant expression of sst is not always related to the biochemical response to SSAs. Headache is a common
A 79-Year-Old Woman With Headache and Acromegaly.
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[Acromegaly. Main symptoms: headache, vision disorders, increased acral growth, coarser facial features].
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The analgesic effect and development of dependency to somatostatin analogue (octreotide) in headache associated with acromegaly.
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Acromegaly: a unique human headache model.
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The management of the patient with acromegaly and headache: a still open clinical challenge.
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Rare association of acromegaly with left atrial myxoma in Carney's complex due to novel PRKAR1A mutation.
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Carney complex (CNC) is a rare autosomal dominant syndrome characterized by pigmented lesions of the skin and mucosae along with cardiac, endocrine, cutaneous, and neural myxomatous tumors. Mutations in the PRKAR1A gene have been identified in ∼70% of the CNC cases reported worldwide. A 30-year-old
Characterization of management and outcomes of patients with acromegaly in Vancouver over 30 years.
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OBJECTIVE
The purpose of this study was to characterize the management and outcomes of patients with acromegaly seen in single center in Vancouver, British Columbia, Canada over a 30 year period.
METHODS
The study involved retrospective data collection from charts of patients diagnosed with
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