- Plasma renin activity: 0,5 mL of plasma EDTA - Plasma norepinephrine: 1,3 mL of plasma EDTA - Aldosterone: 0,5 mL of serum - TNF-alpha: 0,5 mL of serum - Interleukin-6: 0,3 mL of serum - Interleukin-10: 0,3 mL of serum - Interleukin-12: 0,5 mL of serum - 10 ml of urine will be centrifuged at 3000 rpm for 10 minutes at 4°C and storage specimens at - 80°C.

Liver Cirrhosis

Acute Kidney Injury

Hepato-Renal Syndrome

University Hospitals Plymouth NHS Trust

RAI & HRS: Relationship Between Relative Adrenal Insufficiency and Failure of Treatment in Hepatorenal Syndrome

RAI & HRS: Relationship Between Relative Adrenal Insufficiency and Failure of Treatment in Hepatorenal Syndrome: A Prospective Pilot Study

Reduction in sCr with terlipressin in patients with hepatorenal syndrome between patients with and without relative adrenal insufficiency. ** Definition of response to treatment: Response to treatment is defined as a reduction of at least 25% from pre-treatment value. Full response is met when final sCr returns to a value lower than 26 µmol/L above the baseline value. Partial response is met when final sCr returns to a value higher than 26 µmol/L above the baseline value. Always with a reduction of sCr of at least 25% from pre-treatment value.

Hospital survival in patients with RAI and HRS. It's expected that patients with RAI and HRS have a higher mortality rate.

Association between bacterial translocation and RAI and response to treatment of hepatorenal syndrome.

Association between degree of inflammation (as measured by inflammatory markers) and response to treatment of hepatorenal syndrome.

Association between circulatory dysfunction and response to treatment in hepatorenal syndrome.

University Hospital Plymouth NHS Trust

Hyponatremia

Buergerspital Solothurn

Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function

Impact of Hyponatremia on Muscle Strength, Gait and Balance, and Cognitive Function: a Prospective Observational Study

A.) Change in muscle strength in kilogram before and after correction of hyponatremia.

B.) Change in results for the Tinetti performance-oriented mobility assessment (POMA) to evaluate static and dynamic balance abilities during and after correction of hyponatremia.

C.) Change in results for the Montreal Cognitive Assessment (MOCA) test to assess mild cognitive impairment before and after correction of hyponatremia.

LINDNER Gregor

Director Dept. of Internal and Emergency Medicine

Bürgerspital Solothurn

Severe Sepsis

Erciyes University Medical School Department of Endocrinology

Comparison of Total, Salivary and Calculated Free Cortisol Levels in Patients With Severe Sepsis

ZULEYHA KARACA

Associate professor

TC Erciyes University

IV injection of 250 micrograms of Synacthen in 1m

Healthy