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antipsychotics/krebs
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Seite 1 von 949 Ergebnisse
Antipsychotic use is inversely associated with gastric cancer risk: A nationwide population-based nested case-control study.
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Neuroleptic treatment and other factors modifying cancer risk in schizophrenic patients.
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In a Danish cohort of schizophrenics consisting of 6,168 patients followed during 1957-1980, the incidence of certain types of cancer has been shown to be significantly decreased (5). From this cohort 30 males with lung cancer, 21 males with bladder cancer, 17 females with cancer of the uterine
Use of antipsychotics and risk of breast cancer: a Danish nationwide case-control study.
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OBJECTIVE
Some antipsychotics increase prolactin levels, which might increase the risk of breast cancer. Existing evidence is conflicting and based on sparse data, especially for the increasingly used second-generation antipsychotics. We conducted a nationwide case-control study of the association
Neuroleptic dose in the management of delirium in patients with advanced cancer.
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Neuroleptics are commonly used in the management of delirium. Limited information is available regarding the dosage requirements and efficacy of neuroleptics in the palliative care setting. We determined the type and dose of neuroleptic use by delirium subtype. The medical records of 99 inpatients
Neuroleptics in the management of delirium in patients with advanced cancer.
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Delirium is the most common and distressing neuropsychiatric syndrome in cancer patients. Few evidence-based treatment options are available due to the paucity of high quality of studies. In this review, we shall examine the literature on the use of neuroleptics to treat delirium in patients with
Atypical antipsychotics and pituitary neoplasms in the WHO database.
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Amisulpride and risperidone are potent dopamine D2 receptor blocking atypical antipsychotics that can cause hyperprolactinemia. Preclinical evidence shows that chronic administration of antipsychotics can cause pituitary adenomas in female mice. To investigate the clinical relevance in this finding,
Low Doses of the Anti-psychotic Drug Aripiprazole Have Strong P-gp-inhibitory Activity and Sensitize Anti-mitotic Drug-resistant Cancer Cells.
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OBJECTIVE
The present study was designed to identify conditions that would increase the sensitivity of resistant cancer cells to anti-mitotic drugs.
METHODS
Previously, we showed that KBV20C cancer cells highly resistant to Halaven® (HAL) were sensitized by co-treatment with fluphenazine (FLU). In
[Prolactin, antipsychotics and breast cancer: is there a connection?].
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BACKGROUND
The use of antipsychotics can result in elevated prolactin levels or hyperprolactinemia. An increasing number of studies suggests that prolactin plays a role in mammary carcinogenesis, leading to concerns about a possible relationship between antipsychotics and breast
[Hyperglycemia due to atypical antipsychotics in cancer patients with delirium].
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We investigated hyperglycemia due to atypical antipsychotics in cancer patients with delirium. Using patient records retrospectively, we investigated 189 cancer patients who were diagnosed with delirium between June 2008 and May 2009. One- hundred fifty-four of the 189 patients used atypical
Psychopharmacology in supportive care of cancer: a review for the clinician: II. Neuroleptics.
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Neuroleptics are frequently used in patients with advanced cancer. Most relevant and practical aspects of their use in supportive cancer care are reviewed, to assist the clinical oncologist and palliative care specialist when prescribing these drugs. This article reviews pharmacological properties,
A case-control study of endometrial cancer after antipsychotics exposure in premenopausal women.
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OBJECTIVE
Most endometrial cancers are related to hormonal imbalance, and antipsychotics are a common cause of hyperprolactinemia. We investigated the possible relation between the use of antipsychotics and the risk of endometrial cancer.
METHODS
A case-control study was conducted on premenopausal
Antipsychotic drugs: pro-cancer or anti-cancer? A systematic review.
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BACKGROUND
Important data was recently published on the potential genotoxic or carcinogenic effects of antipsychotics, as well as on their cytotoxic properties on cancer cells, that must be considered by psychiatrists in the benefit/risk ratio of their prescriptions.
OBJECTIVE
To answer whether or
Antipsychotic Drug Trifluoperazine Suppresses Colorectal Cancer by Inducing G0/G1 Arrest and Apoptosis.
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Repurposing existing drugs for cancer treatment is an effective strategy. An approved antipsychotic drug, trifluoperazine (TFP), has been reported to have potential anticancer effects against several cancer types. Here, we investigated the effect and molecular mechanism of TFP in colorectal cancer
Neuroleptic prescription pattern for delirium in patients with advanced cancer.
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BACKGROUND
Neuroleptics are frequently used by palliative care specialists to treat delirium. In this study, we determined the median daily neuroleptic dose and prescription pattern in a cohort of unselected advanced cancer in-patients with delirium.
METHODS
We retrospectively reviewed the charts of
Using Neuroleptics to Treat Delirium in Dying Cancer Patients at a Cancer Center in Saudi Arabia.
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Neuroleptics are commonly used for treating delirium as a common problem in terminally ill cancer patients. However, prescribing patterns are believed to substantially vary among health professionals. The aim of this study is to determine the pattern of prescribing neuroleptics for treating delirium
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