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Toxic megacolon in children with inflammatory bowel disease: clinical and radiographic characteristics.

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BACKGROUND Toxic megacolon (TMC) denotes a rare clinical syndrome accompanied by colonic dilatation, and is a serious complication of inflammatory bowel disease (IBD). This study assessed the clinical and radiologic characteristics of TMC in children with IBD. METHODS A systematic search identified

Infection and systemic inflammatory response syndrome in older patients in the emergency department: a 30-day risk model.

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OBJECTIVE To build a model to predict 30-day mortality and compare it to prediction based on the Mortality in Emergency Department Sepsis (MEDS) score in patients aged 75 years or older treated for infection and systemic inflammatory response syndrome (SIRS) in the emergency

Evaluation of a novel prognostic score based on thrombosis and inflammation in patients with sepsis: a retrospective cohort study.

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BACKGROUND Inflammation and thrombosis are involved in the development and progression of sepsis. A novel thrombo-inflammatory prognostic score (TIPS), based on both an inflammatory and a thrombus biomarker, was assessed for its ability to predict adverse outcomes of sepsis patients in the emergency

[Acute disseminated encephalomyelitis in children].

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OBJECTIVE Acute disseminated encephalomyelitis (ADEM) is an immune-mediated inflammatory-demyelinating disease, which usually follows an infection or vaccination. It is more frequent in children. In this paper, I will review clinical, diagnosis, treatment, and prognosis data, based on last 10 years

[Generalized form of cerebral actinomycosis].

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The here presented case was a woman 82 years old suffering for many years of arteriosclerotic Parkinson syndrome. During the last 8 months of her life she exhibited excessive talk flow and states of delirium. Twelve days before death she had a generalized attack of convulsions and the consciousness

[Mixed aphasia as a dominating symptom of encephalitis].

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Encephalitis has typically a severe course, with psychotic disorders, consciousness disorders, epileptic seizures and meningal signs. The author describes a case of a young male, in whom dominant symptoms of encephalities were aphasia and headache. These symptoms were accompanied by considerable

Multiple Sclerosis Like Condition in a Patient of Hepatitis C after Treatment with Interferon Alpha: A Case Report.

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Hepatitis C virus affects millions of people around the world. The primary therapy comprises of interferon alpha and ribavarin. The most common side effects of this treatment include flu like symptoms and psychiatric issues. One of the rare complications of the combined therapy is the development of

Hyperammonemic Induced Coma by Bacterial Overgrowth in a Child With Hirschsprung's Disease.

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Cases with Hirschsprung's disease show the functional intestinal obstruction. Obstruction in these patients may lead to bacterial overgrowth with stasis and inflammation of the colon. Bacterial overgrowth can cause hyperammonemia that makes lethargy and loss of conscious and finally admitting in

Detection of human herpesvirus 6 in cerebrospinal fluid of children with possible encephalitis.

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BACKGROUND Encephalitis is swelling and inflammation of brain, usually due to viral infection. Viral encephalitis symptoms could be fever, headache, altered level of consciousness, and seizures. OBJECTIVE The aim of this study was detection of human herpesvirus-6 (HHV-6) DNA in cerebrospinal fluid

A case of suspected MPO-ANCA-related hypertrophic pachymeningitis with atypical presentation.

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A 66-year-old man presented to our emergency department with acute consciousness disorder, headache, and fever. Initial laboratory data indicated a high level of inflammatory reaction. Enhanced magnetic resonance imaging revealed a thickening of the right cranial dura mater on T1-weighted images. We

Neuroinflammation in sepsis: sepsis associated delirium.

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Sepsis-associated delirium (SAD) is a clinical manifestation of the involvement of the central nervous system (CNS) during sepsis. The purpose of this review is to provide a concise overview of SAD including the epidemiology and current diagnostic criteria for SAD. We present in detail the

Postoperative delirium: risk factors and management: continuing professional development.

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OBJECTIVE Postoperative delirium often remains undiagnosed and therefore untreated. The purpose of this continuing professional development module is to identify patients at high risk of developing delirium following non-cardiac surgery and to provide tools to aid in the diagnosis of delirium at the

Cerebral infarction and femoral venous thrombosis detected in a patient with diabetic ketoacidosis and heterozygous factor V Leiden G1691A and PAI-1 4G/5G mutations.

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Cerebral infarction is one of the serious neurological complications of diabetic ketoacidosis (DKA). Especially in patients who are genetically prone to thrombosis, cerebral infarction may develop due to inflammation, dehydration, and hyperviscocity secondary to DKA. A 6-year-old child with DKA is

The pathological presentations of neuro-Behçet disease: a case report and review of the literature.

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OBJECTIVE To report the neuropathologic features of a patient with neuro-Behçet disease and to review the literature. METHODS Herein, we describe a 35-year-old male who fulfills the International Study Group criteria for Behçet disease. RESULTS The patient developed headache and hemiparesis in a

Primary cerebral arteritis in a young girl: an unusual cause of acute recurrent neurological deterioration.

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BACKGROUND Primary angiitis of the central nervous system (PACNS) is an idiopathic, usually recurrent vasculitis confined to the brain. PACNS has been reported rarely in children, although the disease is probably underdiagnosed. METHODS : We report the clinical history of a 3-year-old girl who

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