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Efficacy and safety of oclacitinib for the control of pruritus and associated skin lesions in dogs with canine allergic dermatitis.

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BACKGROUND Oclacitinib (Apoquel(®) ) inhibits the function of a variety of pro-inflammatory, pro-allergic and pruritogenic cytokines that are dependent on Janus kinase enzyme activity. Oclacitinib selectively inhibits Janus kinase 1. OBJECTIVE We aimed to evaluate the safety and efficacy of

Clinical Manifestations, Treatment, and Prevention of Acute Irritant Contact Dermatitis Caused by 2,4-Dichloro-5-Methylpyrimidine Exposure in 64 Cases.

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There are no reported cases of 2,4-dichloro-5-methylpyrimidine (DCP)-induced irritant contact dermatitis (ICD).The aim of the study was to summarize the clinical features, treatment, and protective measures for DCP-induced

Untreated celiac disease in a patient with dermatitis herpetiformis leading to a small bowel carcinoma.

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Usually, celiac disease has a benign course, though the overall morbidity and mortality have increased. Treatment with a gluten-free diet restores the damaged intestinal mucosa. In rare cases a small bowel adenocarcinoma develops. Unfortunately, the clinical presentation is not always recognized and

A systematic review and meta-analysis of the efficacy and safety of cyclosporin for the treatment of atopic dermatitis in dogs.

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The efficacy of cyclosporin A (CsA) for the treatment of canine atopic dermatitis was evaluated based on the systematic review of prospective clinical trials published between 2001 and 2005. Ten studies with adequate design characteristics were included. These studies enrolled 799 dogs, 672 (84%)

Efficacy of cyclosporin in the treatment of atopic dermatitis in dogs--combined results from two veterinary dermatology referral centres.

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OBJECTIVE To evaluate the efficacy of cyclosporin in controlling the clinical signs associated with atopic dermatitis in dogs under Australian field conditions. METHODS A multicentre prospective clinical investigation of the use of cyclosporin in 41 dogs with atopic dermatitis. METHODS Dogs were

Gastrointestinal symptoms in atopic eczema.

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OBJECTIVE To determine the prevalence of gastrointestinal symptoms in children with eczema and the association of such symptoms with the extent of eczema or skin prick test results. METHODS Sixty five children with atopic eczema and a control group matched for age and sex were recruited. Their

Vomiting and Dehydration in a 2-Year-Old.

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A 2-year-old girl with a past medical history of cutaneous mastocytosis and eczema presented with 1 day of yellow-green, nonbloody vomiting, bradycardia, and listlessness. She was evaluated by her pediatrician and sent to the emergency department because of concern for dehydration. In the emergency

Comparison of clinical history and dermatologic findings in 29 dogs with severe eosinophilic dermatitis: a retrospective analysis.

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The medical records and histopathological sections of 29 dogs diagnosed with a unique eosinophilic dermatitis resembling Wells' syndrome were reviewed in an attempt to elucidate the pathogenesis of this syndrome. The medical records were reviewed for information on dermatological lesion appearance,

[Ketotifen in the treatment of pediatric atopic eczema].

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Clinical effectiveness of ketotifen was evaluated in 15 children, aged 1-3 years, affected by atopic eczema likely due to food allergy. The study, lasting 15 weeks, was divided, according to the protocol, as follow: week run-in period with a restrictive diet; 8 week ketotifen therapy (the first 2

[Etiologic implication of foods in atopic dermatitis: evidence against].

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Atopic dermatitis is a typical chronic inflammatory skin disease that usually occurs in individuals with a personal or family history of atopy. Children with atopic dermatitis frequently present IgE-mediated food sensitization, the most commonly involved foods being egg and cow's milk. However,

Dose tapering for ciclosporin in cats with nonflea-induced hypersensitivity dermatitis.

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BACKGROUND Little information is available on the ciclosporin dose-tapering regimen and clinical response in the treatment of feline hypersensitivity dermatitis. OBJECTIVE To test a dose-tapering regimen and assess efficacy and clinical safety for up to 18 weeks. METHODS Eighty-eight client-owned

A case of atopic dermatitis caused by Ascaris lumbricoides infection.

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UNASSIGNED Parasite infections stimulate total and specific IgE production that, in the case of Toxocara canis infection, corresponds to chronic allergic symptoms. There may also be other infections which have similar symptoms, such as Ascaris lumbricoides infection. Ascaris lumbricoides is a large

Celiac Disease and Dermatitis Herpetiformis: National survey indicates delays in diagnosis.

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A national survey of 1937 members of the Canadian Celiac Association was conducted by mail questionnaire in June 1989 to study problems in diagnosing and managing celiac disease (CD) and dermatitis herpetiformis. Although 82% of the 1294 respondents were biopsied, 14% were diagnosed by their

Hypokalemic myopathy in a patient with gluten-sensitive enteropathy and dermatitis herpetiformis Duhring: a case report.

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The case of a 22-year-old patient with symptomatic hypokalemia caused by rhabdomyolysis is presented as a rarely reported complication of gluten-sensitive enteropathy (GSE) and dermatitis herpetiformis Duhring. The patient's myopathy ceased on potassium supplementation and her other complaints

Gastrointestinal disorders in children with atopic dermatitis.

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The aims of this study were to analyze the peculiarities of allergies to food; to determine gastrointestinal disorders, endoscopic signs of mucosal damage and histological lesions of the mucosa and to establish their relation to the extent of atopic dermatitis and its degree of severity. METHODS A

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