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digitalis/epileptischer anfall
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[Adams-Stokes seizures and digitalis-induced bradycardia].
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Extracardiac and coronary vascular effects of digitalis.
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The administration of digitalis glycosides causes a variety of extracardiac effects. In both normal human subjects and in other species, digitalis increases smooth muscle tone of resistance and capacitance vessels. The vasoconstriction is mediated, in part, by a direct action of these glycosides on
The effects of the purinergic system on digitalis-induced epileptiform activity.
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It has been suggested that endogenous chemical substances, such as adenosine, released during a seizure attack, may act as anticonvulsants in vivo. We have investigated electrophysiologically the effects of purinoceptor agonists and antagonists on the epileptiform activity induced by intracortical
Intravenous potassium therapy in ventricular tachycardia and fibrillation with Stokes-Adams seizures secondary to digitalis intoxication.
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Antiarrhythmic plasma concentrations of mexiletine on canine ventricular arrhythmias.
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Antiarrhythmic effects of mexiletine were examined using three canine ventricular arrhythmia models--digitalis-, adrenaline-, and two-stage coronary ligation-induced arrhythmias. The minimum effective plasma concentration for each arrhythmia model was determined. Mexiletine suppressed all the
Woldemar Mobitz and His 1924 classification of second-degree atrioventricular block.
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Woldemar Mobitz, an early 20th century German internist, analyzed arrhythmias by graphing the relationship of changing atrial rates and premature beats to AV conduction. Through an astute mathematical approach, he was able to classify second-degree atrioventricular block into 2 types, subsequently
Magnesium: clinical considerations.
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Magnesium is gaining recognition as a clinically important electrolyte. Hypomagnesemia has been associated with a variety of disorders including seizures, malignant ventricular dysrhythmias, and sudden death. The emergency department patients who are most likely to be magnesium deficient include
Urginea maritima (squill) toxicity.
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A 55 year-old female ingested two bulbs of Urginea maritime (squill) plant as a folk remedy for her arthritic pains. Her past history was significant for Hashimoto thyroiditis and she was hypothyroid upon presentation. Subsequent effects resembling those seen with cardiac glycoside intoxication
The neuropsychiatric ailment of Vincent Van Gogh.
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Vincent Van Gogh is one of the most celebrated creative artists of all time. All his life, he was afflicted by some kind of neurological or psychiatric disorder, which remains a mystery even today. Many historians and his personal physicians believe that he suffered from epilepsy while others felt
[Proceedings: Pacemaker implantation bradycardia and cardiac insufficiency. Preliminary report].
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The longterm effects of pacemaker therapy have been investigated in 337 patients with bradycardia and congestive heart failure with or without Adams-Stokes syncope. The cumulative survival rate in patients with Adams-Stokes seizures without congestive heart failure (group I) is markedly better than
New antiarrhythmic agents. 4. 1'-(Aminoalkyl)-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-pyrrolidine-2',5'-dione derivatives.
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A series of 33 1'-(Aminoalkyl)-1,2,3,4-tetrahydronaphthalene-1-spiro-3'-pyrrolidine-2',5'-dione derivatives was tested for antiarrhythmic and toxic effects in mice and dogs. In mice, 31 compounds produced some protection against chloroform-induced tachyarrhythmias at subcutaneous doses of 100 mg/kg,
Dangers in the use of some potent drugs.
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The chief dangers reported with some common drugs are reviewed. Hazards of antibiotic therapy include: the increasing incidence of sensitization to penicillin with occasional anaphylactic reactions; aplastic anemia with chloramphenicol, and the poor tolerance of infants for chloramphenicol;
Anesthesia for arterial switch operation in simple transposition of the great arteries: experience at Siriraj Hospital.
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Anesthetic management of cardiac patients with complete transposition of the great arteries (TGA) undergoing arterial switch operation (ASO) is challenging. The anesthetic course and perioperative problems were studied. A prospective data collection study of 87 patients was performed between January
Doctor Gachet, in the kitchen, with the foxglove
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Vincent van Gogh (1853-1890) is one of the most famous artists in the world. During his 10-year career as an artist, he created more than 850 paintings. These works of art are now displayed in museums around the globe. It is therefore even more surprising that van Gogh sold just one painting during
Hypomagnesemia: characterization of a model of sudden cardiac death.
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OBJECTIVE
We sought to compare the incidence of sudden death in rats treated with magnesium-deficient and control diets and to address the electrophysiologic characteristics associated with these end points.
BACKGROUND
Although magnesium deficiency is associated with an increased incidence of sudden
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