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15 Ergebnisse
Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
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BACKGROUND OF THE INVENTION
Treatment of human cancer is an area of clinical medicine which remains fraught with complications and which often presents an array of suboptimal treatment choices. For example, prostate cancer, which is the most common cancer in men and the second leading cause of
Use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer
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FIELD OF THE INVENTION
The present invention relates to a novel use of diterpene compounds as a therapeutic agent for the treatment of inflammatory disease, immunological disease or cancer.
BACKGROUND OF THE INVENTION
Exposure of human tissue or cells to harmful stimuli such as lipopolysaccharide
Use certain diterpene compounds in the treatment of androgen receptor-associated diseases
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FIELD OF THE INVENTION
This invention relates to the use of certain types of diterpene compounds for inhibiting activities of androgen receptors and methods of using those compounds for treatment of androgen receptor-associated diseases, including prostate cancer, benign prostate hypertrophy,
Use of compounds isolated from Euphorbia neriifolia for treating cancer and/or thrombocytopenia
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The present disclosure relates to novel use of compounds isolated from Euphorbia neriifolia for manufacturing a medicament or a pharmaceutical composition for treating cancer and/or thrombocytopenia.
2. Description of Related Art
The leaves
Purified flavonoid and diterpene 5.alpha.-reductase inhibitors from thuja orientalis for androgen-related diseases
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BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to therapeutics of androgenetic diseases containing as active ingredients the nonsteroidal 5.alpha.-reductase inhibitors that have been obtained by fractioning the extracts of crude drugs including Thuja orientalis,
Method of producing a taxane-type diterpene and a method of obtaining cultured cells which produce the taxane-type diterpene at a high rate
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TECHNICAL FIELD
This invention relates to a method of producing a taxane-type diterpene including taxol which is useful as a therapeutic agent for ovarian cancer, mammary cancer, lung cancer and the like, and a method of obtaining cultured cells which produce the taxane-type diterpene at a high
Method of producing a taxane-type diterpene and a method of obtaining cultured cells which produce the taxane-type dilterpene at a high rate
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TECHNICAL FIELD
This invention relates to a method of producing a taxane-type diterpene including taxol which is useful as a therapeutic agent for ovarian cancer, mammary cancer, lung cancer and the like, and a method of obtaining cultured cells which produce the taxane-type diterpene at a high
Treatment of prostate cancer
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FIELD OF THE INVENTION
The present invention relates generally to chemical agents useful in treatment and prophylaxis of prostate cancer or a related cancer or condition or in the amelioration of symptoms resulting from or facilitated by prostate cancer or a related cancer or condition in a
Pimarane diterpenes from Anisochilus verticillatus
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a National Phase of PCT/IN2012/000544, filed 6 Aug. 2012, which claims priority from Indian Application No. 2226/DEL/2011, filed 5 Aug. 2011, the disclosures of which are all incorporated herein by reference.
TECHNICAL FIELD OF
Tricyclic diterpene derivatives
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FIELD OF THE INVENTION
The invention relates to chemical compounds and pharmaceutical compositions, including novel chemical compounds and pharmaceutical compositions thereof, useful in the treatment of various diseases and disease states. The invention also relates to methods of synthesizing
Use of non-irritating or slightly irritating and/or promoting diterpene alcohol and of derivatives thereof as antineoplastic preparations
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The invention concerns new antineoplastic preparations, as well as a process for the preparation of their active components.
For therapeutic application are used antineoplastic preparations which are characterized in that they contain as an active antineoplastic component non- or slightly irritating
Topical use of ingenol-3-angelate or a salt thereof to treat skin cancer
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FIELD OF THE INVENTION
The present invention relates generally to chemical agents useful in the treatment and prophylaxis of inflammatory conditions or in the amelioration of symptoms resulting from or facilitated by an inflammatory condition in a mammalian animal including human and primate,
Derivatives of hypoestoxide and related compounds
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CROSS REFERENCE TO RELATED APPLICATIONS
Expressly incorporated herein by reference are U.S. Pat. Nos. 5,801,193, 5,994,328, 6,001,871 and 6,242,484, PCT WO 98/46222 and previously application, U.S. Ser. No. 09/298,653, now abandoned.
BACKGROUND OF THE INVENTION
Field of the Invention
This invention
Method of use of diterpenoid derivatives as anticancer agents
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FIELD OF THE INVENTION
The present invention relates to a group of derivatives synthesized based on the ent-kaurane diterpenoid flexicaulin A and the methods to synthesize such diterpenoid derivatives. The invention also relates to the chemical entities of such synthetic diterpene compounds in the
Method of use of diterpenoid derivatives as anticancer agents
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FIELD OF THE INVENTION
The present invention relates to a group of derivatives synthesized based on the ent-kaurane diterpenoid flexicaulin A and the methods to synthesize such diterpenoid derivatives. The invention also relates to the chemical entities of such synthetic diterpene compounds in the
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