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endometriosis/phosphatase

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ArtikelKlinische VersuchePatente
Seite 1 von 93 Ergebnisse
OBJECTIVE Is phosphatase of regenerating liver-3 (PRL-3) associated with increased motility of endometriotic cells from endometrioma? CONCLUSIONS Elevated PRL-3 promotes cytoskeleton reorganization, cell migration and invasion of endometrial stromal cells (ESCs) from

Acid phosphatase locus 1 genetic polymorphism, endometriosis, and allergy.

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Recent studies suggest that acid phosphatase locus 1 (ACP1) could be involved in T-cell antigen receptor signaling and in immune disorders. The present study shows that the ACP1( *)C allele, which is associated with elevated enzymatic activity, is significantly more common in women with

Phosphatase of regenerating liver-3: a novel and promising marker in human endometriosis.

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OBJECTIVE To investigate the expression of phosphatase of regenerating liver-3 (PRL-3) in ectopic, eutopic, and normal endometria and explore its relationship with endometriosis. METHODS A clinical retrospective and molecular study. METHODS Department of obstetrics, gynecology, and reproductive

Placental-type alkaline phosphatase in peritoneal fluid of women with endometriosis.

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Alkaline phosphatase (ALP) activities were studied in peritoneal fluid obtained from patients with untreated endometriosis and control women who had normal pelves. The patients (n = 18) had significantly higher total ALP (8.65 +/- 5.69 mU/mg, p less than 0.01) and thermostable ALP (0.28 +/- 0.23

Inhibition of dual specificity phosphatase-2 by hypoxia promotes interleukin-8-mediated angiogenesis in endometriosis.

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OBJECTIVE How does hypoxia-mediated down-regulation of dual specificity phosphatase-2 (DUSP2) promote endometriotic lesion development? CONCLUSIONS Inhibition of DUSP2 by hypoxia enhances endometriotic lesion growth via promoting interleukin-8 (IL-8)-dependent angiogenesis. BACKGROUND Angiogenesis

Association of the protein tyrosine phosphatase non-receptor 22 polymorphism (PTPN22) with endometriosis: a meta-analysis.

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UNASSIGNED To evaluate PTPN22 C1858T polymorphism and the risk of endometriosis. UNASSIGNED A meta-analysis of 10 published case-control studies (from four articles), with a total sample of 971 cases and 1,181 controls, was performed. We estimated risk (odds ratio and 95% confidence intervals) of
Peritoneal fluid from 35 women with endometriosis and from 34 control women was aspirated at laparoscopy and analyzed. No differences in prostanoid levels were found. The peritoneal fluid volume, macrophage concentration, macrophage content, and content of activated macrophages as measured by acid

Evaluation of biodegradable microspheres containing nomegestrol acetate in a rat model of endometriosis.

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We assessed the efficacy of biodegradable microspheres (MSs) containing nomegestrol acetate (NOMAC) for treatment of endometriosis in a rat model and investigated its preliminary mechanism of action. Sprague-Dawley rats with surgically implanted endometrial autografts were divided randomly into four

A randomized comparative study of the effect of leuprorelin acetate depot and danazol in the treatment of endometriosis.

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BACKGROUND Administration of superactive agonistic analog of gonadotropin-releasing hormone (GnRH) has shown to induce a paradoxic and reversible suppression of gonadotropins, so that gonadal steroid concentrations are suppressed and hypoestrogenemia is induced. In order to compare the efficacy and

[Mifepristone following conservative surgery in the treatment of endometriosis].

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OBJECTIVE To compare the efficacy and safety of mifepristone and danazol after conservative surgery in the treatment of patients with endometriosis. METHODS Sixty-one patients with endometriosis (RAFS stage I-IV ) after conservative surgery were treated orally either with mifepristone 10 mg/d (group
BACKGROUND The microenvironmental biomarkers of different subtypes of ovarian cancers arising from endometriosis have not been studied in Taiwan. Their expression can help in understanding the carcinogenic mechanism. METHODS Our study used immunohistochemistry to compare the expression of estrogen
Inflammation in the ovary, including ovulation and pelvic inflammatory disease, has been proposed to play a role in the pathogenesis of ovarian cancer. Endometriotic lesions trigger a local inflammatory reaction and have been reported to be associated with an increased risk of epithelial ovarian

Differential micro ribonucleic acid expression profiling in ovarian endometrioma with leuprolide acetate treatment.

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OBJECTIVE Micro ribonucleic acids (miRNAs) play an important pathological role in endometriosis. Leuprolide acetate, an analog of gonadotropin-releasing hormone, is widely used to treat endometriosis; however, the molecular mechanisms involved in endometriotic tissue regression remain unclear. We

[Relation between macrophages in peritoneal fluid of endometriosis and infertility].

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Peritoneal fluid was collected from 18 endometriosis-associated infertile patients and 14 unexplained infertile women. The cells were counted in a hemacytometer and subjected to morphologic analysis. The phagocytic activity on Candida Albicans and on Sperms was evaluated and the activity of acid

Treatment of endometriosis with leuprorelin acetate depot: a German multicentre study.

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During the past decade, the development of various gonadotrophin-releasing hormone (Gn-RH) agonists, which induce reversible hypo-oestrogenism has opened a new area in the medical management of endometriosis. In an open, multicentre phase III study, the efficacy, tolerance and safety of the Gn-RH
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