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N-acyl amino acid derivatives, a method for the preparation thereof, a pharmaceutical composition and use thereof as anti-allergic, anti-inflammatory and hypolipidemic agents
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The present invention relates to the field of bioorgmic chemistry and concerns N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof, novel processes for synthesis of said compounds as well as pharmaceutical compositions based on them and use thereof in medicine as
N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form anti-allergic, anti-inflammatory and hypolipidemic agents
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The present invention relates to the field of bioorganic chemistry and concerns N-acyl derivatives of amino acids and pharmaceutically acceptable salts thereof, novel processes for synthesis of said compounds as well as pharmaceutical compositions based on them and use thereof in medicine as
Phenylpyrrole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/JP2012/081744 filed Dec. 7, 2012, claiming priority based on Japanese Patent Application No. 2011-268561 filed Dec. 8, 2011, the contents of all of which are incorporated herein by
Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient
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TECHNICAL FIELD
The present invention relates to a nitrogen-containing bicyclic compound or a pharmacologically acceptable salt thereof and a pharmaceutical composition comprising it as active ingredient.
More specifically, the present invention relates to (1) a compound of formula (I)
##STR00002##
Probiotic compositions for improving metabolism and immunity
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SEQUENCE LISTING
The instant application contains a Sequence Listing which has been submitted electronically in ASCII format and is hereby incorporated by reference in its entirety. Said ASCII copy, created on Oct. 13, 2017, is named 191Sequence_ST25.txt and is 4,393 bytes in size.
FIELD
The
Process for producing milk fractions rich in secretory immunoglobulins
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FIELD OF THE INVENTION
The present invention concerns a process for producing compositions that are rich in secretory IgA (S-IgA) by fractionating milk containing S-IgA. Such compositions may be used in particular for one or more of treating and/or preventing infections and/or inflammation of the
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein
R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl,
R.sub.b
Indolylmaleimide derivatives
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The present invention relates to indolylmaleimide derivatives, process for their production and pharmaceutical compositions containing them.
More particularly the present invention provides a compound of formula I
##STR00002## wherein R.sub.a is H; CH.sub.3; CH.sub.2--CH.sub.3; or isopropyl, R.sub.b
Animal with the mass expression of human gene and test method by using the animal
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This is a 371 U.S. National Stage Application of PCT JP00/06963, filed Oct. 5, 2000.
TECHNICAL FIELD
The invention of this application relates to a human gene over-expressing animal, and to various test methods using the animal. More precisely, the invention of this application relates to a
Alicyclic imidazoles as H3 agents
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FIELD OF THE INVENTION
The present invention is directed to alicyclic imidazoles which interact with the histamine H.sub.3 receptor as agonists, antagonists or inverse agonists; pharmaceutically active compositions containing such compounds; and the use of such compounds in formulations for the
Phenoxypiperidines and analogs thereof useful as histamine H.sub.3 antagonists
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FIELD OF THE INVENTION
The present invention relates to phenoxypiperidines and analogs thereof useful as histamine H.sub.3 antagonists. The invention also relates to pharmaceutical compositions comprising said compounds and their use in treating inflammatory diseases, allergic conditions, diabetes,
Heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists
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FIELD OF THE INVENTION
The present invention relates to heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists. The invention also relates to pharmaceutical compositions comprising said compounds and their use in treating inflammatory diseases,
Heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists
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FIELD OF THE INVENTION
The present invention relates to heteroatom-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists. The invention also relates to pharmaceutical compositions comprising said compounds and their use in treating inflammatory diseases,
Carbon-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists
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FIELD OF THE INVENTION
The present invention relates to carbon-linked substituted piperidines and derivatives thereof useful as histamine H.sub.3 antagonists. The invention also relates to pharmaceutical compositions comprising said compounds and their use in treating inflammatory diseases, allergic
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