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intracranial aneurysm/hypoxie
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Seite 1 von 32 Ergebnisse
[Effects of hypoxia preconditioning on serum NGB and S-100B in patients with intracranial aneurysm surgery].
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OBJECTIVE
To study the clinical effects of hypoxia preconditioning (HPC) and its effects on serum neuroglobin (NGB) and S-100B level in the patients undergoing intracranial aneurysm surgery.
METHODS
Forty patients scheduled to intracranial aneurysm surgery were randomly.divided into 2 groups: HPC
[Anesthesia for patients with a cerebral aneurysm who showed hypoxemia during surgery].
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Two patients showed hypoxia and brain swelling during craniotomy under the diagnosis of ruptured cerebral aneurysm. It was not possible to continue the operation due to brain swelling. Postoperatively, they were diagnosed as pulmonary embolism by Tc-scintigraphy. Re-operation was carried out after
Upregulated signaling pathways in ruptured human saccular intracranial aneurysm wall: an emerging regulative role of Toll-like receptor signaling and nuclear factor-κB, hypoxia-inducible factor-1A, and ETS transcription factors.
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BACKGROUND
Aneurysmal subarachnoid hemorrhage, almost always from saccular intracranial aneurysm (sIA), is a devastating form of stroke that affects the working-age population. Cellular and molecular mechanisms predisposing to the rupture of the sIA wall are largely unknown. This knowledge would
Biochemical changes related to hypoxia during cerebral aneurysm surgery: combined microdialysis and tissue oxygen monitoring: case report.
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OBJECTIVE
The objective of this study was to monitor brain metabolism on-line during aneurysm surgery, by combining the use of a multiparameter (brain tissue oxygen, brain carbon dioxide, pH, and temperature) sensor with microdialysis (extracellular glucose, lactate, pyruvate, and glutamate). The
Improvement of hypoxia during early surgery for ruptured intracranial aneurysm: a retrospective evaluation.
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[A case of ventricular fibrillation during emergency clipping operation for cerebral aneurysm].
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A 59 year-old woman with subarachnoid hemorrhage underwent emergency neck clipping of cerebral aneurysm. Her preoperative examination showed atrial fibrillation, pulmonary edema and hypokalemia. Ventricular fibrillation developed immediately after clipping of the aneurysm and recurred 7 times
Preoperative hypoxemia in conscious patients after subarachnoid hemorrhage.
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We retrospectively examined partial arterial pressure of oxygen (Pao2) afer subarachnoid hemorrhage (SAH), adjusted for patient-related risk factors for hypoxemia in 51 adult patients with no disturbance of consciousness undergoing surgery for clipping of intracranial aneurysms. A control group of
Intra-operative monitoring by means of somatosensory evoked potentials during cerebral aneurysms surgery.
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During cerebral aneurysms surgery, brain tissue may suffer for global or local ischemia due to deliberate hypotension and surgical manoeuvres. Somatosensory evoked potentials (SEPs) can detect functional derangements consequent to hypoxia, before a permanent brain damage is produced. Forty two
miR-4735-3p regulates phenotypic modulation of vascular smooth muscle cells by targeting HIF-1-mediated autophagy in intracranial aneurysm.
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Intracranial aneurysm (IA) is recognized as a lethal form of cerebrovascular disease mainly featured with a modulated phenotype of vascular smooth muscle cells (SMCs). It is generally believed that enhanced SMC proliferation and migration capabilities are the main characteristics in this process. In
[Artificial arterial hypotension during surgical treatment of intracranial aneurysms].
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In studying the content of lactic and pyruvic acids in the cerebrospinal fluid of 31 patients during operation for intracranial aneurysms under halothane anesthesia, the authors established that the performance of these operations under protection of deep (40 mm Hg) and prolonged (up to 2 hrs 25
Investigating the efficacy of a new intravenous (IV) nanoemulsified sevoflurane/arginine formulation for maintenance of general anesthesia for embolization of cerebral aneurysm.
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The aim of this research investigation was to profound analysis the mitigating impact of sevoflurane/arginine post-molding on cerebral ischemia-reperfusion damage in rats. The authors fabricated emulsions fusing sevoflurane, perfluorooctyl bromide as a settling specialist, and mixes of arginine
Hydrogen Suppresses Hypoxia/Reoxygenation-Induced Cell Death in Hippocampal Neurons Through Reducing Oxidative Stress.
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OBJECTIVE
Deep hypothermic circulatory arrest (DHCA) is a cerebral protection technique that has been used in the operations involving the aortic arch and brain aneurysm for decades. We previous showed that DHCA treated rats developed a significant oxidative stress and apoptosis in neurons. We here
A case of cerebral aneurysm rupture and subarachnoid hemorrhage associated with air travel.
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During air travel, passengers are exposed to unique conditions such as rapid ascent and descent that can trigger significant physiological changes. In addition, the cabins of commercial aircraft are only partially pressured to 552-632 mmHg or the equivalent terrestrial altitudes of 1,500-2,500 m
Long non-coding RNA HIF1A-AS1 is upregulated in intracranial aneurysms and participates in the regulation of proliferation of vascular smooth muscle cells by upregulating TGF-β1.
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Long non-coding (lnc)RNA hypoxia inducible factor 1α-antisense RNA 1 (HIF1A-AS1) not only participates in different types of malignancies, but also serves pivotal roles in thoracic aortic aneurysms, which suggests its possible involvement in intracranial aneurysms. Therefore, the present study aimed
Microenvironment of ruptured cerebral aneurysms discovered using data driven analysis of gene expression.
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