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inula obtusifolia/antimykotikum
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[Research on antifungal activity of flowers and leaves of Inula viscosa (Asteraceae)].
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The authors carried out a preliminary screening about the in vitro antifungal activity of some extracts of flowers and leaves of Inula viscosa obtained with different solvents. All extracts showed antifungal activity against dermatophytes and Candida species. The best results were obtained with
Antimycotic activities of selected plant flora, growing wild in Lebanon, against phytopathogenic fungi.
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Petroleum ether (PE) and methanolic extracts of nine wild plant species were tested in vitro for their antimycotic activity against eight phytopathogenic fungi. The efficacy of PE extracts against all pathogens tested was higher than that of methanolic extracts. Wild marjoram (Origanum syriacum) PE
Use of Moroccan medicinal plant extracts as botanical fungicide against citrus blue mould.
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The aim of this work was to find an alternative to chemical fungicides currently used in the control of postharvest citrus fruit diseases. In this study, we screened eight Moroccan medicinal and aromatic plants extracted with petroleum ether, chloroform, ethyl acetate and methanol for their
Antioxidant and antifungal activity of different extracts obtained from aerial parts of Inula crithmoides L.
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The total phenolic content, antioxidant and antifungal activities of three Inula crithmoides extracts (n-hexane, methylene chloride and MeOH) were investigated. The methanolic extract showed the highest total phenolic content. In the DPPH assay, the methanolic and hexane extracts exhibited the
Antifungal activity of essential oils from leaves and flowers of Inula viscosa (Asteraceae) by Apulian region.
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Some essential oils from several plants (Artemisia verlotorum, Lavandula augustifolia, Ocimum gratissimum) have proved to have acaricidal, antifungal and antibacterial activity. Inula viscosa Ait. (Asteraceae), a plant growing spontaneously in the Mediterranean area, is currently used by popular
In vivo therapeutic potential of Inula racemosa in hepatic ischemia-reperfusion injury following orthotopic liver transplantation in male albino rats.
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Hepatic ischemia-reperfusion (I/R) injury mainly occurs following hepatic resection and liver transplantation and cause severe liver damage, organ injuries, and dysfunction. Pro-inflammatory cytokines that promote injury are released when kupffer cell activates after getting induced by I/R.
Total polyphenol content, in vitro antifungal and antioxidant activities of callus cultures from Inula crithmoides.
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This is the first report on the antioxidant and antifungal activities of callus cultures from Inula crithmoides L. (Asteraceae). Callus cultures were initiated from leaf sections, on initial culture MS basal medium supplemented with various concentrations of 2,4-D (2,4-dichlorophenoxyacetic acid),
Antifungal activity of plant extracts against dermatophytes.
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The aqueous extracts (15 micrograms ml-1 medium) of 22 plants used in folkloric medicine in Palestine were investigated for their antifungal activity and minimum inhibitory concentrations (MICs) against nine isolates of Microsporum canis, Trichophyton mentagrophytes and Trichophyton violaceum. The
Isolation and Identification of a New Antifungal Sesquiterpene Lactone from Inula viscosa.
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A new sesquiterpene - tayunin - has been isolated and purified from powdered leaves of INULA VISCOSA (L.) Ait. The chemical structure was determined by 1D and 2D NMR analysis, and IR and MS. Tayunin inhibits the growth of MICROSPORUM CANIS at a concentration of 10 microg/ml and TRICHOPHYTON RUBRUM
Assessment of therapeutic effect of Inula heterolepsis Boiss in alcoholic rats.
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An aqueous extract from the root of Inula heterolepsis Boiss was prepared and then tested for its ability to treat experimentally induced alcoholic hepatic injury in rats. Alcoholic rats were divided into two groups. The first group of rats were given 200 mg/kg/day plant extract. Repeated doses of
Modulation of Cox-1, 5-, 12- and 15-Lox by popular herbal remedies used in southern Italy against psoriasis and other skin diseases.
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Acanthus mollis (Acanthaceae), Achillea ligustica, Artemisia arborescens and Inula viscosa (Asteraceae) are used in Southern Italy against psoriasis and other skin diseases that occur with an imbalanced production of eicosanoids. We here assessed their in vitro effects upon 5-, 12-, 15-LOX and COX-1
A new validated HPTLC method for quantitative determination of 1, 5-dicaffeoylquinic acid in Inula crithmoides roots.
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1, 5-Dicaffeoylquinic acid (1, 5-DCQA), a potent HIV-1 integrase inhibitor, is currently undergoing an evaluation as a promising novel HIV therapeutic agent. This work aims at developing an accurate, rapid, repeatable and robust HPTLC method for the determination of 1, 5-DCQA in its natural sources.
1β-Hydroxyalantolactone, a sesquiterpene lactone from Inula japonica, attenuates atopic dermatitis-like skin lesions induced by 2,4-dinitrochlorobenzene in the mouse.
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BACKGROUND
1β-Hydroxyalantolactone (IJ-5) is a sesquiterpene lactone compound isolated from Inula japonica Thunb (Asteraceae). Sesquiterpene lactones have been shown to modulate many processes that influence inflammatory reactions.
OBJECTIVE
The present study examines the protective effect of IJ-5
Effect of Inula viscosa extract on chitin synthesis in dermatophytes and Candida albicans.
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An antimycotic effect of an extract from Inula viscosa leaves was demonstrated affecting chitin synthesis in dermatophytes and Candida albicans. The antimycotic effect was compared to the effect caused by miconazole nitrate--an antifungal drug. The inhibition effect on chitin synthesis was not
1-o-acetylbritannilactone (ABL) inhibits angiogenesis and lung cancer cell growth through regulating VEGF-Src-FAK signaling.
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The search for safe, effective and affordable therapeutics against non-small cell lung cancer (NSCLC) and other lung cancers is important. Here we explored the potential effect of 1-o-acetylbritannilactone (ABL), a novel extract from Inula britannica-F, on angiogenesis and lung cancer cell growth.
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