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Seite 1 von 70 Ergebnisse
Delay of Iris flower senescence by protease inhibitors.
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Visible senescence of the flag tepals in Iris x hollandica (cv. Blue Magic) was preceded by a large increase in endoprotease activity. Just before visible senescence about half of total endoprotease activity was apparently due to cysteine proteases, somewhat less than half to serine proteases, with
Daffodil flowers delay senescence in cut Iris flowers.
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Visible symptoms of tepal senescence in cut Iris x hollandica (cv. Blue Magic) flowers were delayed by placing one cut daffodil flower (Narcissus pseudonarcissus, cv. Carlton) in the same vase. Addition of mucilage, exuded by daffodil stems, to the vase water had the same effect as the flowering
Uveitogenic proteins isolated from bovine iris and ciliary body.
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Experimental autoimmune anterior uveitis (EAAU) is an animal model for acute anterior uveitis in humans. Previously, we have shown that EAAU can be induced in Lewis rats by a protein(s) associated with ocular melanin. The present study was designed to further purify the pathogenic antigen. Melanin
Prostaglandin E2 and F2 alpha binding sites in the bovine iris ciliary body.
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OBJECTIVE
To determine the regional distribution and selectivity of prostaglandin E2 (PGE2) and prostaglandin F2 alpha (PGF2 alpha) specific binding sites in membrane preparations from bovine iris ciliary body.
METHODS
Bovine eyes were obtained fresh from a local abattoir. Whole irides were
Iris protein antibodies in serum of patients with juvenile rheumatoid arthritis and uveitis.
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Homogenates of bovine iris were fractionated by gel filtration chromatography, and the column-eluted proteins were probed with pooled sera obtained from patients with pauciarticular juvenile rheumatoid arthritis (JRA). The serum pool prepared from patients with pauciarticular JRA and a history of
Experimental autoimmune anterior uveitis. Induction with melanin-associated antigen from the iris and ciliary body.
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OBJECTIVE
This study was designed to investigate an animal model of uveitis that resembles anterior uveitis in humans after immunization with iris-ciliary body antigen.
METHODS
Male Lewis rats 6 to 8 weeks of age were immunized with the buffer- and detergent-insoluble bovine iris-ciliary body
Immune reconstitution inflammatory syndrome: a report of TB-IRIS after switching from efavirenz to dolutegravir
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In 2016, the World Health Organization adopted dolutegravir (DTG)-based antiretroviral therapy as an alternative first-line treatment of HIV after many clinical trials showed that it was more effective, better tolerated and more protective than efavirenz and boosted protease inhibitors against
Increased oxidative stress, lipid peroxidation and protein degradation trigger senescence in Iris versicolor L. flowers.
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Dynamics in various physiological and biochemical aspects were studied during various stages (I-tight bud stage to VI-senescent stage) of flower development in Iris versicolor. Floral diameter, fresh & dry mass and water content increased during flower opening and decreased towards senescence.
Prostaglandin receptors coupled to adenylyl cyclase in the iris-ciliary body of rabbits, cats and cows.
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Stimulation of adenylyl cyclase by prostaglandin (PG) receptor agonists was examined in the iris-ciliary body of rabbits, cats and cows. Iris-ciliary bodies were incubated with or without agonists in Krebs pyruvate buffer containing protease and cyclooxygenase inhibitors. The formation of cAMP in a
Adenine type and diphenyl urea derived cytokinins improve the postharvest performance of Iris germanica L. cut scapes.
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An experiment was designed to evaluate the effect of various adenine derived cytokinins (kinetin and 6-benzylaminopurine) and diphenyl urea cytokinin (thidiazuron) on the postharvest performance of cut scapes of Iris germanica. Flower scapes were harvested with the oldest bud at '1 day before
Ritonavir/saquinavir plus one nucleoside reverse transcriptase inhibitor (NRTI) versus indinavir plus two NRTIs in protease inhibitor-naive HIV-1-infected adults (IRIS study).
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OBJECTIVE
To compare the efficacy, tolerability and safety of a ritonavir 400 mg/saquinavir hard gel fomulation 400 mg twice daily versus an indinavir 800 mg once every 8 h containing first-line protease inhibitor (PI) treatment regimen.
METHODS
Open, randomized, multicentre clinical trial. PI-naive
Cell cycle arrest and biochemical changes accompanying cell death in harmful dinoflagellates following exposure to bacterial algicide IRI-160AA.
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Bacteria may play a role in regulating harmful algal blooms, but little is known about the biochemical and physiological changes associated with cell death induced by algicidal bacteria. Previous work characterized an algicidal exudate (IRI-160AA) produced by Shewanella sp. IRI-160 that is effective
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury.
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Complement research experienced a renaissance with the discovery of a third activation route, the lectin pathway. We developed a unique model of total lectin pathway deficiency, a mouse strain lacking mannan-binding lectin-associated serine protease-2 (MASP-2), and analyzed the role of MASP-2 in two
Lysosomal protease cathepsin D; a new driver of apoptosis during acute kidney injury.
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Acute kidney injury (AKI) is an abrupt reduction in kidney function caused by different pathological processes. It is associated with a significant morbidity and mortality in the acute phase and an increased risk of developing End Stage Renal Disease. Despite the progress in the management of the
Use of boosted protease inhibitors reduces Kaposi sarcoma incidence among male veterans with HIV infection.
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BACKGROUND
Kaposi sarcoma (KS) incidence has decreased since combination antiretroviral therapy (cART). However, effects of cART type and duration on KS remain difficult to interpret secondary to KS-associated immune reconstitution inflammatory syndrome (IRIS).
METHODS
We performed a retrospective
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