Deutsch
Albanian
Arabic
Armenian
Azerbaijani
Belarusian
Bengali
Bosnian
Catalan
Czech
Danish
Deutsch
Dutch
English
Estonian
Finnish
Français
Greek
Haitian Creole
Hebrew
Hindi
Hungarian
Icelandic
Indonesian
Irish
Italian
Japanese
Korean
Latvian
Lithuanian
Macedonian
Mongolian
Norwegian
Persian
Polish
Portuguese
Romanian
Russian
Serbian
Slovak
Slovenian
Spanish
Swahili
Swedish
Turkish
Ukrainian
Vietnamese
Български
中文(简体)
中文(繁體)
neurodegenerative diseases/phosphatase
Der Link wird in der Zwischenablage gespeichert
Seite 1 von 18 Ergebnisse
Phosphate mimics and methods of treatment using phosphatase inhibitors
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
FIELD OF THE INVENTION
The present invention relates to, inter alia, novel trifluoromethyl sulfonyl and trifluoromethyl sulfonamido compounds, their physiologically acceptable salts and prodrugs, which modulate the activity of protein phosphatases and uses thereof. The invention also relates to the
Protein tyrosine phosphatase inhibitors and methods of use thereof
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
FIELD OF THE INVENTION
This invention relates to the field of protein tyrosine phosphatase inhibition.
BACKGROUND OF THE INVENTION
This invention relates to a novel class of phosphonic acid derivatives that are inhibitors of PTP-1B.
Reversible protein tyrosine phosphorylation, coordinated by the
Protein tyrosine phosphatase inhibitors and methods of use thereof
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
FIELD OF THE INVENTION
This invention relates to the field of protein tyrosine phosphatase inhibition.
BACKGROUND OF THE INVENTION
This invention relates to a novel class of phosphonic acid derivatives that are inhibitors of PTP-1B.
Reversible protein tyrosine phosphorylation, coordinated by the
Regulation of human protein phosphatase IIc-like enzyme
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
TECHNICAL FIELD OF THE INVENTION
The invention relates to the regulation of human protein phosphatase IIC-like enzyme activity for therapeutic effects.
BACKGROUND OF THE INVENTION
The protein phosphorylation/dephosphorylation cycle is one of the major regulatory mechanisms employed by eukaryotic
Treatment of neurodegenerative diseases
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
This application is U.S. National Phase of International Application PCT/AU2007/000391, filed Mar. 29, 2007 designating the U.S., and published in English as WO 2007/109851 on Oct. 4, 2007, which claims priority to U.S. Provisional Application No. 60/787,240 filed Mar. 29, 2006.
FIELD OF THE
PPM1E proteins and nucleic acids as targets for neurodegenerative diseases
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
BACKGROUND OF THE INVENTION
The present invention relates to assays and methods for identifying or for testing agents which are modulators of a serine-threonine phosphatase PPM1E and can be used for treating and/or preventing neurodegenerative disorders.
The present invention relates to methods of
Immunophilin-binding agents prevent glutamate neurotoxicity associated with vascular stroke and neurodegenerative diseases
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
FIELD OF THE INVENTION
The invention relates to the use of inhibitors of calcineurin to prevent glutamate neurotoxicity.
BACKGROUND OF THE INVENTION
Nitric oxide (NO) has been demonstrated to mediate neuronal relaxation of intestines (Bult (1990) Nature, 345:346-347; Gillespie (1989) Br. J.
Pharmaceutical composition for preventing or treating neurodegenerative diseases
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
CROSS-REFERENCE TO RELATED APPLICATIONS
This application claims priority of Korean Patent Applications Nos. KR 10-2015-0100430, filed Jul. 15, 2015 and KR 10-2015-0100481, filed Jul. 15, 2015, the contents of each of which are hereby incorporated by reference into the application.
REFERENCE TO A
Methods of evaluating phosphatase inhibitors
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
CROSS-REFERENCE TO A RELATED APPLICATION
The present application is a National Stage (371) of International Application PCT/JP02/11365, filed on Oct. 31, 2002, which claims priority to Japanese Patent Application No. JP 2001-335833, filed on Oct. 31, 2001.
TECHNICAL FIELD
The present invention
Nucleic acid encoding a phosphatase 2C that interacts with Fe 65
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
BACKGROUND OF THE INVENTION
The present invention relates to the discovery of protein--protein interactions that are involved in the pathogenesis of neurodegenerative disorders, including Huntington's Disease, Parkinson's Disease, dementia and Alzheimer's Disease (AD). Thus, the present invention is
Substituted carboxylic acids
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to substituted carboxylic acids and more specifically to such compounds that are useful in the treatment of diabetes. More specifically, it relates to such compounds that are capable of inhibiting Protein tyrosine
Substituted amino carboxylic acids
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to substituted carboxylic acids and more specifically to such compounds that are useful in the treatment of syndrome X (consisting of such abnormalities as obesity, dyslipidemia, hypercoagulation, hypertension, insulin
Phenyl substituted carboxylic acids
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to phenyl substituted carboxylic acids and more specifically to such compounds that are useful in the treatment of syndrome X (consisting of such abnormalities as obesity, dyslipidemia, hypercoagulation, hypertension,
Phenyl substituted carboxylic acids
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to phenyl substituted carboxylic acids and more specifically to such compounds that are useful in the treatment of syndrome X (consisting of such abnormalities as obesity, dyslipidemia, hypercoagulation, hypertension,
Substituted amino carboxylic acids
Nur registrierte Benutzer können Artikel übersetzen
Einloggen Anmelden
BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to substituted carboxylic acids and more specifically to such compounds that are useful in the treatment of syndrome X (consisting of such abnormalities as obesity, dyslipidemia, hypercoagulation, hypertension, insulin
Die vollständigste Datenbank für Heilkräuter, die von der Wissenschaft unterstützt wird
- Arbeitet in 55 Sprachen
- Von der Wissenschaft unterstützte Kräuterkuren
- Kräutererkennung durch Bild
- Interaktive GPS-Karte - Kräuter vor Ort markieren (in Kürze)
- Lesen Sie wissenschaftliche Veröffentlichungen zu Ihrer Suche
- Suchen Sie nach Heilkräutern nach ihrer Wirkung
- Organisieren Sie Ihre Interessen und bleiben Sie über Neuigkeiten, klinische Studien und Patente auf dem Laufenden
Geben Sie ein Symptom oder eine Krankheit ein und lesen Sie über Kräuter, die helfen könnten, geben Sie ein Kraut ein und sehen Sie Krankheiten und Symptome, gegen die es angewendet wird.
* Alle Informationen basieren auf veröffentlichten wissenschaftlichen Forschungsergebnissen
