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TECHNICAL FIELD
The present invention belongs to the field of biotechnology, and more particularly, to a ribonucleic acid aptamer having an inhibitory effect on non-small cell lung cancer and a pharmaceutical composition comprising the same.
BACKGROUND ART
Cancer has become one of the leading causes
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to proteins which contain amino acid sequences that bind to 3'-untranslated regions of mRNAs, particularly mRNA sequences containing "instability sequences" and sequences affecting the translation and localization of
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to proteins which contain amino acid sequences that bind to 3'-untranslated regions of mRNAs, particularly mRNA sequences containing "instability sequences" and sequences affecting the translation and localization of
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to proteins which contain amino acid sequences that bind to 3'-untranslated regions of mRNAs, particularly mRNA sequences containing "instability sequences" (Shaw et al, Cell (1986) 46: 659-667).
2. Discussion of the
REFERENCE TO A SEQUENCE LISTING
This application refers to a "Sequence Listing" listed below, which is provided as an electronic document entitled "Sequence.txt" (9 kb created on Nov. 30, 2017) which is incorporated herein by reference in its entirety.
BACKGROUND OF THE INVENTION
Prostate cancer
REFERENCE TO A SEQUENCE LISTING
This application refers to a "Sequence Listing" listed below, which is provided as an electronic document entitled "Sequence.txt" (8 kb created on Nov. 5, 2016) which is incorporated herein by reference in its entirety.
BACKGROUND OF THE INVENTION
Prostate cancer
BACKGROUND OF THE INVENTION
1. Field of the Invention
The present disclosure relates to treatments for cancers. More particularly, the disclosure relates to treating cancer by use of novel double-stranded short interfering nucleic acid that inhibits the translation of Aurora-A mRNA.
2. Description
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is
BACKGROUND OF THE INVENTION
Ribonucleic acid (RNA) is essential to the processes which allow translation of the genetic code to form proteins necessary for all cellular functions, both in normal and neoplastic cells. While the genetic code structurally exists as deoxyribonucleic acid (DNA), it is