patients with emesis gravidarum who take a chewing gum with vitamin C (verum) "ad libitum" several times daily for 2 weeks

patients with emesis gravidarum who take chewing gum without vitamin C (placebo) "ad libitum" several times daily for 2 weeks

patients with emesis gravidarum who do not use chewing gum during the study phase

Hyperemesis Gravidarum

Nausea Gravidarum

Vitamin C Deficiency

Using a chewing gum with 150mg vitamin C (per piece/gum) for 14 days "ad libitum"

Pregnan-C-Gum(R) chewing gum

Using a chewing gum without vitamin C (per piece/gum) for 14 days "ad libitum"

Placebo chewing gum

Medical University of Vienna, Dept. of Obstetrics and Gynecology

Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum

Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum: a Randomized Controlled Trial

validated questionnaire describing individual nausea

Alex Farr, MD PhD

Assistant Professor, Consultant Physician

Medical University of Vienna

Xerostomia

Asialia

Hyposalivation

Mouth Dryness

Aqualief

Placebo

Fondazione IRCCS Istituto Nazionale dei Tumori

Effects of Aqualief® in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer

Evaluate the Effects of Aqualief® Mucoadhesive Tablets (a Food Supplement Based on Carnosine and Hibiscus) in Patients Who Developed Oral Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer

Change of saliva production, without mechanical stimulation.

Report from patients the facility to use and palatability of the product

Helsinn Healthcare SA

Latis S.r.l.

randomized, double blind, placebo controlled, cross over study

Gum type was standardized with all subjects receiving sugar-free peppermint-flavored gum.
The patients in the chewing gum group, gum chewing began the morning of postoperative day 1. Patients chewed gum (one stick) 3 times daily in the morning, afternoon, and evening at least 5 min. The administration of the therapy was implemented by ward nursing staff and recorded in the patients file. All gum-chewing patients completed their course of gum chewing until bowel function.

Postoperative Ileus

İzmir Tepecik training and research hospital

Influence of Gum Chewing on Postoperative Bowel Activity After Complete Staging Surgery for Gynecological Malignancies

The main outcome variable of the study was postoperative flatus pass time (hours from end of operation). Participants will be followed for the duration of the flatus pass time, an expected average of 48 hours

Participants will be followed for the duration of hospital stay, an expected average of 3 weeks

gastrointestinal disturbance such as nausea, abdominal cramping, abdominal distension, rate of vomiting

time to first bowel movement (hours from end of operation).Participants will be followed for time to first bowel movement, an expected average of 48 hours hours from end of operation

The main outcome variable of the study was postoperative flatus pass time (hours from end of operation).Participants will be followed for the duration of the first defaecation time, an expected average of 72 hours

sorbitol/erbrechen

Chewing Gum Containing Vitamin-c to Treat Emesis Gravidarum

Effects of Aqualief® in Patients With Xerostomia as Consequence of Radiotherapy for Head and Neck Cancer

Influence of Gum Chewing on Postoperative Bowel Activity After Complete Staging Surgery for Gynecological Malignancies

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