spondylarthropathies/unwohlsein und ermüdung

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Fatigue contributes to work productivity impairment in patients with axial spondyloarthritis: a cross-sectional UK study.

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OBJECTIVE To determine factors associated with absenteeism, presenteeism, work productivity loss (WPL), and daily activity impairment in UK patients with AxSpA using standardised measures. METHODS 490 patients with AxSpA completed (1) Work Productivity and Impairment questionnaire (WPAI), providing

[The patient complains of spinal pain or fatigue and weakness. How do I recognize whether their cause is spondylarthrosis, the patients age or multiple myeloma?].

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Multiple myeloma has varied manifestations which resemble common patient complaints and that is why this disease is typically not diagnosed until it reaches an advanced stage. Spinal pains can be an expression of deformative and discogenous changes, but also a symptom of multiple myeloma. Pains in

Towards a multidimensional patient reported outcome measures assessment: development and validation of a questionnaire for patients with ankylosing spondylitis/spondyloarthritis.

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OBJECTIVE To assess the validity, reliability and responsiveness to change of a patient self-reported questionnaire that can assess construct outcome measures of patients with ankylosing spondylitis (AS)/spondyloarthritis. METHODS The questionnaire was developed by integrating information obtained

Chronic widespread pain in spondyloarthritis.

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The pain associated with spondyloarthritis (SpA) can be intense, persistent and disabling. It frequently has a multifactorial, simultaneously central and peripheral origin, and may be due to currently active inflammation, or joint damage and tissue destruction arising from a previous inflammatory

Update upon efficacy and safety of etanercept for the treatment of spondyloarthritis and juvenile idiopathic arthritis.

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TNF-α inhibitors have demonstrated efficacy both as monotherapy and in combination with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of chronic inflammatory immune-mediated diseases such as rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis (AS),

Flare in axial spondyloarthritis: investigation of meaningful changes in symptomatic outcome measures.

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OBJECTIVE To assess symptomatic outcomes associated with flare after discontinuation of non-steroidal anti-inflammatory drugs (NSAIDs) in axial spondyloarthritis (axSpA). METHODS Patients with NSAID-refractory axSpA discontinued NSAIDs, restarted if symptoms recurred, and self-recorded Bath

[Depression and Anxiety in Spondyloarthritis: Prevalence and Relationship with Clinical Parameters and Self-Reported Outcome Measures].

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To assess the prevalence of depression and anxiety among patients with spondyloarthritis.One hundred patients with spondyloarthritis attending the rheumatology outpatient unit were enrolled. Duration of morning stiffness, pain/fatigue visual-analogue-scale,

Remission in Axial Spondyloarthritis: Developing a Consensus Definition.

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To reach a consensus on the tools available to evaluate disease activity in patients with axial spondyloarthritis (axSpA), and to develop a consensus definition of remission in axSpA.A modified Delphi method was used. A scientific committee proposed

Measuring participation in people with spondyloarthritis using the social role participation questionnaire.

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OBJECTIVE People with spondyloarthritis (SpA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) have identified the importance of understanding how their disease and its treatment impacts on their social roles. This requires a reliable and valid standardised measure, and this study

No deterioration in health-related quality of life in patients with axial spondyloarthritis followed for 5 years in ordinary outpatient clinics in the biological treatment era.

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Axial spondyloarthritis (ax-SpA) causes pain, fatigue, stiffness, loss of physical function and impaired health-related quality of life (HRQOL).The study aimed to explore the changes in HRQOL over 5 years in patients with ax-SpA and to identify baseline

Traditional Chinese medicine (TCM) collaborative care for patients with axial spondyloarthritis (AcuSpA): protocol for a pragmatic randomized controlled trial.

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Axial spondyloarthritis (AxSpA) is a chronic disease which results in fatigue, pain, and reduced quality of life (QoL). Traditional Chinese medicine (TCM), especially acupuncture, has shown promise in managing pain. Although a TCM collaborative model of care (TCMCMC) has been studied

Fatigue in ankylosing spondylitis.

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OBJECTIVE To review the literature on fatigue in ankylosing spondylitis (AS), the tools of its measurement, relation with the other parameters of the disease, treatment and its relation with exercises. METHODS Medline, Embase, Pascal and Cochrane library databases were searched with the keywords

Pain in spondyloarthritis: A neuro-immune interaction.

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Pain in spondyloarthritis is usually attributed to inflammation. However, treatment with potent biologic agents that control inflammation does not always control the pain. Pain is hence likely to be multifactorial. Fatigue is another prominent feature of this condition which again tends to respond

Alendronate in bone cement: fatigue life degraded by liquid, not by powder.

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Bisphosphonates have the potential to reduce osteolysis, a phenomenon that has been postulated to play a key role in aseptic loosening of total joint replacements. Bisphosphonates may contribute to the in vivo longevity of total joint replacements. Some authors have suggested there are decreases in

Late onset spondylarthropathy: clinical and biological comparison with early onset patients.

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OBJECTIVE To compare the clinical, radiological, and biological profile of patients presenting late onset spondylarthropathy (LOSPA) with patients with early onset spondylarthropathy (EOSPA). METHODS During the period April 1987 to April 1995 a retrospective chart review of inpatients and

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