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tartaric acid/zahnkaries

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ArtikelKlinische VersuchePatente
15 Ergebnisse

Synthesis and Kinetics of Highly Substituted Piperidines in the Presence of Tartaric Acid as a Catalyst.

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The synthesis of highly substituted piperidine from the one-pot reaction between aromatic aldehydes, anilines and β-ketoesters in the presence of tartaric acid as a catalyst has been investigated in both methanol and ethanol media at ambient temperature. Different conditions of temperature and
This work deals with multicomponent complex formation of vinpocetine (VP) with beta-cyclodextrin (betaCD), sulfobutyl ether beta-cyclodextrin (SBEbetaCD) and tartaric acid (TA), in the presence or absence of water-soluble polymers, in aqueous solution. Complexation was monitored by phase-solubility

Imidazo[2,1-b]benzothiazoles. II. Synthesis and antiinflammatory activity of some imidazo[2,1-b]benzothiazoles.

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3-[2-[p-(Un)substituted phenyl]imidazo [2,1-b]benzothiazol-3- yl]propionic acid derivatives (2a--e) were prepared via the interaction of the corresponding 2-[p-(un)substituted phenyl]imidazo[2,1-b]benzothiazoles (1a--e) with acrylic acid in the presence of acetic anhydride and acetic acid.
The demand for sublingual tablets has been growing during the previous decades especially for drugs with extensive hepatic first-pass metabolism. Vinpocetine, a widely used neurotropic agent, has low oral bioavailability due to its poor aqueous solubility and marked first-pass metabolism.

Certain carboxylic acid buffers can destabilize β-cyclodextrin complexes by competitive interaction

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Thirteen buffers were investigated for their effect on the binding of adamantanol to β-cyclodextrin and hydroxypropyl-β-cyclodextrin. Stability constants for the β-cyclodextrin complex ranged from 14,800 to 46,000 M-1, and the binding enthalpies were between -23.2 and -10.4 kJ/mole.
Background: Dental caries originates due to the localized dissolution of the hard tissues of teeth mainly caused by acids, developed by the presence of micro-organisms in the biofilm (dental plaque) on the surface of teeth causing
Reaction of (1 R,3 S)-(+)-camphoric acid (H2cam) with uranyl ions under solvo-hydrothermal conditions and in the presence of bulky countercations gave five chiral complexes of varying dimensionality. [Cu( R,S-Me6cyclam)][UO2(Hcam)2(HCOO)2] (1)
The structures of two brucinium (2,3-dimethoxy-10-oxostrychnidinium) salts of the alpha-hydroxy acids L-malic acid and L-tartaric acid, namely brucinium hydrogen (S)-malate pentahydrate, C23H27N2O4+.C4H5O5-.5H2O, (I), and anhydrous brucinium hydrogen (2R,3R)-tartrate, C23H27N2O4+.C4H5O6-,(II), have

The effect of oxalic acid incorporation on the setting time and strength of a glass-ionomer cement.

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Oxalic acid and its metal oxalate salts have been used extensively in dentistry in a range of applications: as desensitisers, in cavity preparation, and as bonding agents. This study investigated the influence of oxalic acid upon the working time, initial setting time, 24-h hardness and compressive

Theoretical and experimental investigations on miconazole/cyclodextrin/acid complexes: molecular modeling studies.

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The inclusion of miconazole into cyclodextrin cavity has been demonstrated by different authors. Preliminary studies have shown which fragment of the molecule is involved in the inclusion. In the present study, AM1 approximate molecular orbital calculations have been performed on several

Dissolution of ibuprofen enantiomers from coprecipitates and suspensions containing chiral excipients.

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The purpose of this research was to evaluate the stereospecific interaction of ibuprofen with chiral excipients such as hydroxypropyl-beta-cyclodextrin (HPCD), tartaric acid, sucrose, hydroxypropylmethylcellulose (HPMC), methylcellulose (MC), and a nonchiral excipient, citric acid. Coprecipitates of

In vitro fluoride release and the antibacterial effect of glass ionomers containing chlorhexidine gluconate.

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Fluoride release from glass-ionomers (GI) may be important for the prevention of secondary caries. The addition of chlorhexidine gluconate (CHX) to glass-ionomer cement (3%) adds an effect that enables it to be used as a varnish for the temporary coating of surfaces at risk for caries. This study
The emerging prevalence of multidrug-resistance in Gram-negative pathogens, due to conventional antimicrobial therapeutics, has led the researchers to emphasize on development of alternative novel strategies to suppress the bacterial virulence and pathogenicity through inhibition of quorum sensing

Chorda tympani and lingual nerve responses to astringent compounds in rodents.

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A wide variety of compounds in foods and beverages produce astringent sensations when introduced into the oral cavity. There is controversy, however, whether "astringency," with its associated puckering and drying sensations, is a fundamental taste quality or is a tactile sensation. To address this

Identification of a foldaxane kinetic byproduct during guest-induced single to double helix conversion.

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An aromatic oligoamide sequence was designed and synthesized to fold in a single helix having a large cavity and to behave as a host for a dumbbell-shaped guest derived from tartaric acid. NMR, molecular modeling, and circular dichroism (CD) evidence demonstrated the rapid formation of this 1:1
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