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Seite 1 von 43 Ergebnisse
Cyclosporin A in the treatment of severe Behçet's uveitis.
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Twelve patients with active Behçet's uveitis with marked deterioration of visual acuity in at least one eye were treated with cyclosporin A (CyA). An initial improvement in the severity of ocular inflammation and systemic features occurred in all cases and persisted until the dose was reduced or the
Azathioprine as a treatment option for uveitis in patients with juvenile idiopathic arthritis.
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OBJECTIVE
To investigate the therapeutic value of azathioprine as monotherapy or combined with other immunosuppressive drugs for uveitis in patients with juvenile idiopathic arthritis (JIA).
METHODS
A retrospective multicentre study including 41 children with JIA (28 (68.2%) female) with unilateral
[Immunosuppressive therapy with mycophenolate mofetil (CellCept) in treatment of uveitis].
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BACKGROUND
Severe forms of uveitis can often only be managed sufficiently with systemic immunosuppression. All available drugs are known for their relative high rate of side-effects. Mycophenolate mofetil (MMF), an immunosuppressant successfully used in management after organ transplantation and
Low-dose methotrexate treatment in noninfectious uveitis resistant to corticosteroids.
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A total of 14 patients (10 women and 4 men) ranging in age from 18 to 56 years who presented with active chronic noninfectious uveitis were treated with low-dose methotrexate (MTX). All patients had failed to respond to previous systemic corticosteroid therapy. MTX therapy was initiated in 8
[Acute tubulo-interstitial nephritis combined with uveitis (clinical case and review of the literature)].
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The authors have presented a review of literature and their own data on acute tubulointerstitial nephritis combined with uveitis in a patient aged 47. In foreign literature this combination is defined as a separate syndrome (TIN-uveitis or TINU). The development of nonspecific symptoms (fatigue,
[Tubulo-interstitial nephritis and uveitis syndrome--TINU syndrome].
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Acute tubulo-interstitial nephritis and uveitis (TINU syndrome) in a 53-year-old woman is reported. This rare syndrome was described 27 years ago by Dobrin et al. Since then about 50 cases have been described. The syndrome can appear at any age but most patients are under 20 years; about 75% are
[Tubulointerstitial nephritis-uveitis syndrome (TINU syndrome)].
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For 10 weeks a 25-year-old man had been suffering from tiredness, fatigue, nausea and a 16 kg weight loss. Erythrocyte sedimentation rate (83/133 mm), serum C-reactive protein (5.5 mg/dl) and creatinine (5.05 mg/dl) were all elevated. He also had proteinuria (1120 mg daily), sterile leukocytosis and
The use of low dose methotrexate in children with chronic anterior and intermediate uveitis.
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OBJECTIVE
To assess the efficacy of low dose methotrexate (MTX) therapy for children with chronic anterior and intermediate uveitis.
METHODS
A retrospective case review of 10 children who received MTX for chronic uveitis at a tertiary referral centre was performed. The following data were recorded
Short course of cyclophosphamide therapy may reduce recurrence in patients with tubulointerstitial nephritis and uveitis syndrome.
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We report a 43-year-old woman with tubulointerstitial nephritis and uveitis syndrome (TINU syndrome) presented with a 5-day complaint of chills and fever, anorexia, nausea, and vomiting. She had elevated BUN and creatinine and urinalysis revealed decreased concentration, proteinuria, hematuria, and
Tubulointerstitial nephritis and uveitis: report of a rare syndrome.
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Tubulointerstitial nephritis and uveitis (TINU) is a rare syndrome with unknown pathogenesis. Data have shown a higher prevalence in female gender. We present a man with tubulointerstitial nephritis and uveitis syndrome and antitubular antibody. A 23-year-old man presented with a history of weight
Tubulointerstitial nephritis and uveitis (TINU) syndrome in a 52-year-old female: a case report and review of the literature.
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Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare entity first described in 1975, affecting mainly young women and adolescents. We present a case of a 52-year-old female patient (one of the oldest in the literature) who complained of fever, anorexia, nausea, and vomiting. After she
A rare case of acute renal failure due to tubulointerstitial nephritis and uveitis syndrome successfully treated with steroid.
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We hereby describe a 49-year-old woman with acute renal failure due to tubulointerstitial nephritis and uveitis (TINU) syndrome. This patient presented with vomiting and nausea and was found to have chronic uveitis, elevated creatinine, and interstitial nephritis. The combination of
FK506 treatment of noninfectious uveitis.
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OBJECTIVE
We studied the clinical effects of the immunosuppressive agent FK506 in patients with noninfectious uveitis.
METHODS
This study was designed as a multicenter open clinical trial in Japan. Sixteen patients with noninfectious uveitis who had visited the Uveitis Survey Clinic of the Yokohama
A Comprehensive Review of mTOR-Inhibiting Pharmacotherapy for the Treatment of Non-Infectious Uveitis.
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Non-infectious uveitis is a sight-threatening inflammatory disease that often necessitates prolonged use of high-dose corticosteroids, resulting in significant systemic side effects. There is a need for efficacious steroid-sparing immunomodulatory therapy for these patients, and the mTOR inhibitors
Cyclosporin-A therapy in severe uveitis of Behçet's disease.
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OBJECTIVE
Cyclosporine-A (CSA) combined with corticosteroid therapy was administered to 12 patients with severe Behçet's uveitis who were resistant to colchicine or cytotoxic therapy.
METHODS
Previous colchicine or cytotoxic therapies were tapered off one month before CSA therapy. All patients were
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