Nasal irrigation BID with normal saline and 1/2 teaspoon baby shampoo

COVID 19

Saline Nasal Irrigation

Saline with 1/2 teaspoon Baby Shampoo Nasal Irrigation.

Saline with Baby Shampoo Nasal Irrigation

Vanderblt University Medical Center

Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19

Viral RNA will be extracted using a standard Qiagen viral RNA isolation kit. An established, high-throughput CoV genome sequencing pipeline will be used to perform overlapping long-range RT-PCR across the viral genome for each viral genome proposed in this project.

Evaluate microbial sequence data in the context of SARS-CoV-2 infection status to determine taxonomic profiles and their distributions within and between samples.

Perform qPCR Analysis to asses viral copy number.

Identify symptom burden during the course of the disease via self-report

Identify temperature during the course of the disease via self-report

Kyle Kimura

Resident Physician, PGY-3

Vanderbilt University Medical Center

Patients enrolled will be randomized to one of three treatment groups (1. control- no intervention, 2. intervention 1 - nasal saline irrigations BID, 3. intervention 2- nasal saline irrigations with ½ teaspoon surfactant (Johnson's baby shampoo) BID).

Participants will receive two lozenges containing probiotic bacteria and cranberry.

Participants will receive a control two lozenges containing no probiotic bacteria.

Oral Disease

A half of the participants will be randomly allocated to the probiotics group. They will receive two probiotics lozenge before falling asleep for 8 weeks. Clinical examination will be conducted before study and after 8 weeks.

Probiotics

A half of the participants will be randomly allocated to the placebo group. They will receive two no probiotics lozenge before falling asleep for 8 weeks. Clinical examination will be conducted before study and after 8 weeks.

Placebo - No probiotics

Dorota Olczak-Kowalczyk

Effect of Probiotic on Oral Health of Children

Effect of Probiotic Lactobacillus Salivarius and Cranberry on Oral Health of Children

During control tests saliva will be applied to the medium for identification and detailed quantification of S. mutans bacteria. After the incubation, the number of bacteria will be expressed - taking into account the degree of saliva dilution - as the number of colony-forming unit (CFU) in 1 ml of saliva.

Medical University of Warsaw

NutroPharma

Those who smoke at least one cigarette a day.

Those who have not smoked for at least one week when the sample is collected.

Smoking

Avioq

Evaluation of An Oral Fluid Collection Device

Collection and Testing of Human Oral Fluid Samples/VioOne OF Sample Collection Device

ELISA assay in comparison with the Mass-spec method will be used to detect the presence of nicotine in the oral fluid samples collected with the VioOne collection device.

vaccinium arctostaphylos/zahnkaries

Impact of Nasal Saline Irrigations on Viral Load in Patients With COVID-19

Effect of Probiotic on Oral Health of Children

Evaluation of An Oral Fluid Collection Device

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