Bioscience, Biotechnology and Biochemistry 2005-Jun
Effects of fenugreek seed extract in obese mice fed a high-fat diet.
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It was found that fenugreek seed extract reduced the body weight gain induced by a high-fat diet in obese mice. The extract decreased plasma triglyceride gain induced by oil administration. The major component of the extract, 4-hydroxyisoleucine, also decreased plasma triglyceride gain. Consequently, fenugreek seed extract is expected to prevent the obesity induced by a high-fat diet.