Zeitschrift fur Naturforschung. Section C, Biosciences
Evidence for the participation of a 5-oxo-prolinase in degradation of glutathione in Nicotiana tabacum.
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During degradation of glutathione in tobacco suspension cultures substancial amounts of 5-oxo-proline are formed in vivo as well as in crude cell homogenates in vitro. The existance of a 5-oxo-prolinase that catalyzes the conversion of 5-oxo-proline to glutamic acid was demonstrated in tobacco cells, grown with glutathione as sole sulfur source.