Frequency of allergic asthma and common aeroallergens sensitization in Pakistani patients of bronchial asthma.
Λέξεις-κλειδιά
Αφηρημένη
OBJECTIVE
To determine the frequency of allergic asthma and 18common causative aeroallergens sensitisation among patients of bronchial asthma.
METHODS
This descriptive cross-sectional study was conducted at the Armed Forces Institute of Pathology, Rawalpindi, Pakistan, from March 2014 to March 2016, and comprised clinically-diagnosed adult patients of bronchial asthma referred from various hospitals of Rawalpindi and Islamabad. Detailed history of each patient was recorded. Serum total immunoglobulin E level was determined using enzyme-linked immunosorbent assay. Skin prick test for 18 common aeroallergens was performed. SPSS 20 was used for data analysis..
RESULTS
Of the 105 patients, 62 (59.05%) were males and 43(40.95%) were females. The overall mean age for males and females was 29.9±10.2 years and 28.7±7.0 years respectively. Overall mean serum total immunoglobulin E was 285.01±241.39IU/ml. Frequency of atopy/allergic asthma was 59(56.2%) and patients with raised total immunoglobulin E had more chance of developing allergic asthma than those having normal immunoglobulin E(p <0.05). Frequency of allergen sensitisation was the highest with house dust mite 35(33.3%), followed by paper mulberry 33(31.4%) and grass 28(26.7%) cases.s.
CONCLUSIONS
Prevalence of allergic asthma was high and the most common allergen causing highest sensitisation was house dust mite.
