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BACKGROUND
Diluted sodium hypochlorite represents an inexpensive and widely available topical antiseptic, but there are no tolerability and efficacy data in veterinary dermatology.
OBJECTIVE
To determine the in vivo antibacterial effect and tolerability of topical diluted bleach application and to
A trial was made comparing the effects of efficient and thorough removal of plaque and debris alone, and with a daily antiseptic mouthwash. The results showed considerable variation but no significant difference in gingival inflammation between hygienic treatment and a daily mouthwash with
Different types of in-situ forming implants based on poly(lactic-co-glycolic acid) (PLGA) for the controlled dual release of an antiseptic drug (chlorhexidine) and an anti-inflammatory drug (ibuprofen) were prepared and thoroughly characterized in vitro. N-methyl-pyrrolidone (NMP) was used as
BACKGROUND
Since the discovery that periodontal diseases are caused by microbial plaque the interest of many scientists has been focused on oral antiseptics. There are very few mouthrinses with oral antiseptic effect originally designed in our country. One of these is Ozosept
Opening of purulent foci in children with pyo-inflammatory diseases (PID) of soft tissues often leads to detection of staphylococcus aureus in the monoculture and different associations of this microbe with gram-negative bacteria in amounts exceeding the "critical level" responsible for the
Clinical and experimental studies of polydimethyldiallylammonium chloride (PDMDAAC) were carried out in order to select the optimal concentration and composition of the preparation. 1% PDMDAAC solution showed high antiseptic activity and can be used for local therapy of the periodontal inflammations
Data sourcesPubMed, the Cochrane Library and Web of Science databases.Study selectionRandomised controlled trials (RCTs) providing information on the effectiveness of oral sprays on plaque or gingival inflammation and published in English were considered.Data extraction and synthesisTwo reviewers
Recently, bioactive peptides have attracted attention for their therapeutic applications in the pharmaceutical industry. Among them, antimicrobial peptides are candidates for new antibiotic drugs. Since pseudin-2 (Ps), isolated from the skin of the paradoxical frog Pseudis paradoxa, shows
OBJECTIVE
To review the effectiveness of antiseptic oral sprays on oral health.
METHODS
Three electronic databases (PubMed, Cochrane Library and Web of Science) were systematically searched to identify relevant studies. Only randomized controlled trials (RCTs) comparing the effect of oral sprays to
The study's aim was to assess the clinical outcome 6 and 12 months after a nonsurgical treatment of peri-implantitis per se or in conjunction with a combination of local antiseptic and anti-inflammatory treatment.Included were 69 patients with Clinical and experimental studies of polydimethyldiallylammonium chloride (PDMDAAC) experimentally validated the choice of optimal concentration and composition of this agent. The results indicate a high antiseptic activity of 1% PDMDAAC and the possibility of using it in local therapy of
Toll-like receptor 4 (TLR4) induced proinflammatory signaling has been directly implicated in severe sepsis and represents an attractive therapeutic target. Herein, we report our investigations into the structure-activity relationship and preliminary drug metabolism/pharmacokinetics study of β-amino