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TECHNICAL FIELD
The invention herein is directed to an expansion of the use of selective inhibitors of cyclooxygenase-2 and of natural substances which inhibit cyclooxygenase-2.
BACKGROUND OF THE INVENTION
Prostaglandins are important mediators of inflammation that are produced at elevated levels in
BACKGROUND
The present invention relates to dietary food supplements that are useful for the relief of pain or inflammation, and also for the inhibition of biochemical pathways related to pain or inflammation transmission. These food supplements contain flavonoids, and more particularly, certain
BACKGROUND
The present invention relates to dietary food supplements that are useful for the relief of pain or inflammation, and also for the inhibition of biochemical pathways related to pain or inflammation transmission. These food supplements contain flavonoids, and more particularly, certain
FIELD OF THE INVENTION
This invention is in the field of preventing or treating cardiovascular disorders. More specifically, this invention relates to the use of aldosterone antagonist and cyclooxygenase-2 inhibitor combination therapy in preventing or treating cardiovascular disease including
FIELD OF THE INVENTION
This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to co-administration of an inhibitor of cyclooxygenase-2 and a 5-lipoxygenase inhibitor for treating inflammation and inflammation-related disorders, such as arthritis.
BACKGROUND
FIELD OF THE INVENTION
This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to co-administration of an inhibitor of cyclooxygenase-2 and a leukotriene A.sub.4 hydrolase inhibitor for treating inflammation and inflammation-related disorders, such as
FIELD OF THE INVENTION
This invention is in the field of antiinflammatory pharmaceutical agents and specifically relates to co-administration of an inhibitor of cyclooxygenase-2 and a leukotriene A.sub.4 hydrolase inhibitor for treating inflammation and inflammation-related disorders, such as
BACKGROUND OF THE INVENTION
Research into the mechanism of inflammatory pain led to the discovery of the biochemical pathway associated with inflammation. One such example of chronic inflammatory pain is osteoarthritis. The elucidation of this pathway led to the association of the pro-inflammatory
BACKGROUND OF THE INVENTION
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used because of their anti-inflammatory and analgesic activity. It is commonly recognized that NSAIDs exert their effect by blocking the activity of cyclooxygenase (COX), also known as prostaglandin G/H synthase
This application is a U.S. national stage of PCT/EP2011/052325 filed on Feb. 17, 2011 which claims priority to and the benefit of Italian Application No. MI2010A000318 filed on Feb. 26, 2010, the contents of which are incorporated herein by reference.
FIELD OF INVENTION
The present invention relates
FIELD OF THE INVENTION
This invention relates to therapeutic compositions that exhibit anti-inflammatory properties and inhibit cyclooxygenase. The compositions are useful for treating osteoarthritis and rheumatoid arthritis, as well as pain related to connective tissue trauma or injury.
BACKGROUND
FIELD OF THE INVENTION
This invention relates to therapeutic compositions that exhibit anti-inflammatory properties and inhibit cyclooxygenase. The compositions are useful for treating osteoarthritis and rheumatoid arthritis, as well as pain related to connective tissue trauma or injury.
BACKGROUND
FIELD OF THE INVENTION
This invention relates to therapeutic compositions that exhibit anti-inflammatory properties and inhibit cyclooxygenase. The compositions are useful for treating osteoarthritis and rheumatoid arthritis, as well as pain related to connective tissue trauma or injury.
BACKGROUND
FIELD OF THE INVENTION
This invention relates to novel cyclooxygenase-2 selective agents, particularly cyclooxygenase-2 inhibitors, useful as imaging probes for positron emission tomography (PET) and single photon emission computed tomography (SPECT), as well as to related diagnostic and therapeutic
FIELD OF THE INVENTION
The invention describes novel nitrosated and/or nitrosylated cyclooxygenase 2 (COX-2) selective inhibitors and novel compositions comprising at least one nitrosated and/or nitrosylated cyclooxygenase 2 (COX-2) selective inhibitor, and, optionally, at least one compound that