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With the recent advances in spinal muscular atrophy therapies, the complete scenario of standard of care and following up is changing not only in the clinical field with new phenotypes emerging but also with new expectations for patients, caregivers and health providers. The actual evidence
BACKGROUND
Early neurological deterioration (END) is an important factor associated with worse clinical outcome in minor strokes. Early magnetic resonance imaging (MRI) findings can provide better sensitivity to delineate stroke pathophysiology and have diagnostic value associated with causative
OBJECTIVE
This study aims to determine the ability of the National Early Warning Score at ICU discharge (NEWSdc) to predict the development of clinical deterioration within 24h.
METHODS
A prospective observational study was conducted. The NEWS was immediately recorded before discharge (NEWSdc). The
After implementation of electronic modified early warning score to engage the rapid response team as a clinical decision support tool, we assessed the knowledge level about and usage of the tool by core staff. We identified a knowledge deficit, planned and implemented an educational intervention,
Frontotemporal lobar degeneration (FTLD) is the third most common cause of cortical dementia, following Alzheimer disease and dementia with Lewy body. Clinical criteria of FTLD were reviewed, and the initial symptoms, early neuropsychological and behavioral characteristics were also reviewed. In our
Current research suggests that amygdalar volumes in patients with Alzheimer's disease (AD) may be a relevant measure for its early diagnosis. However, findings are still inconclusive and controversial, partly because studies did not focus on the earliest stage of the disease. In this study, we
Hospitals can experience difficulty in detecting and responding to early signs of patient deterioration leading to late intensive care referrals, excess mortality and morbidity, and increased hospital costs. Our study aims to explore potential indicators of physiological deterioration by the
Our aim was to revisit the papers published by Scherer 1933 describing four cases of sporadic olivopontocerebellar atrophy (OPCA) thought to represent the earliest description of striatonigral degeneration. One should note that extrapyramidal rigidity associated with OPCA was then considered a type