exanthema/triglyceride

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Άρθρα Κλινικές δοκιμέςΔιπλώματα ευρεσιτεχνίας

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[Middle-aged female presenting with headache, blurred vision and skin rash].

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BACKGROUND Autoimmune hyperlipidemia (AIH) is a rare cause of secondary hyperlipidemia. A few cases of AIH have been reported in multiple myeloma. METHODS A female in her fifties was referred to the outpatient clinic presenting with headache, blurred vision and skin rash. Physical examination with

Efficacy of pentoxifylline in the treatment of pruritic papular eruption of HIV-infected persons.

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BACKGROUND Pruritic papular eruption (PPE) of HIV/AIDS is a common manifestation of HIV infection. Unfortunately, treatments for the unremitting pruritus have yielded only partial relief. OBJECTIVE Our purpose was to assess the clinical efficacy of pentoxifylline in the treatment of pruritus in

Analysis of sebum lipid composition and the development of acneiform rash before and after administration of egfr inhibitor.

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Treatment with an epidermal growth factor receptor inhibitor (egfri) in patients having non-small-cell lung cancer can cause frequent and diverse skin toxicities, an acneiform rash being one of the commonest. Although the exact pathophysiology of this rash and its development mechanisms remain

Niacin improved rigidity and bradykinesia in a Parkinson's disease patient but also caused unacceptable nightmares and skin rash--a case report.

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A patient with Parkinson's disease taking levodopa/carbidopa, selegiline, buproprion, aspirin and niacin had decreased rigidity and bradykinesia when his niacin dose was steadily escalated for treatment of high triglycerides, but ultimately the patient could not tolerate niacin because of severe

Atypical clinical presentation of systemic juvenile idiopathic arthritis or Still's disease: a report of two cases

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Juvenile idiopathic arthritis (JIA) constitutes a group of arthritis of unknown origin that begins before the age of 16 years. Still´s disease is the systemic form of this condition. Its clinical presentation is marked by fever, rash and sometimes joint pain, in the absence of evidence of another

[Clinical evaluation of glimepiride in treatment of type 2 diabetes. Results of a multicenter study].

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In a multicenter study 142 patients (from 8 centers) with type 2 diabetes (77 men and 65 women, mean age 57 +/- 8.5 (SD) yrs, mean duration of diabetes 64.4 +/- 57.7 months, mean BMI 28.7 +/- 3.6 kg/m2) received over 3 months as the only antidiabetic drug glymepiride (Amaryl) once daily before

Safety and efficacy of tocilizumab as monotherapy or in combination with methotrexate in Tunisian patients with active rheumatoid arthritis and inadequate response to disease-modifying anti-rheumatic drugs in conditions close to clinical practice.

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We aimed to assess the safety and efficacy of tocilizumab as monotherapy or in combination with methotrexate in a routine clinical practice setting in Tunisian patients with RA who did not respond to conventional treatment with disease-modifying anti-rheumatic drugs

Guggul for hyperlipidemia: a review by the Natural Standard Research Collaboration.

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OBJECTIVE To evaluate the scientific evidence on guggul for hyperlipidemia including expert opinion, folkloric precedent, history, pharmacology, kinetics/dynamics, interactions, adverse effects, toxicology, and dosing. METHODS Electronic searches were conducted in nine databases, 20 additional

Fate of PCDF/PCB congeners and change of clinical symptoms in patients with Yusho PCB poisoning for 30 years.

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Two mass-food poisonings called Yusho and Yucheng occurred in Japan and Taiwan in 1968 and 1979, respectively. Blood samples from five Yusho patients and three Yucheng patients were collected several times from 1982 to 1998 and from 1980 to 1995, respectively, and analyzed for polychlorinated

[The changes of PCBs and PCDFs as well as symptoms in Yusho patients for 30 years].

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Two mass-food poisonings called Yusho and Yucheng occurred in Western Japan and Taiwan in 1968 and 1979, respectively. Blood samples from 5 Yusho patients and 3 Yucheng patients were collected several times from 1982 to 1998 and from 1980 to 1995, respectively, and analyzed for PCB and PCDF

Ehrlichia-induced hemophagocytic lymphohistiocytosis in two children.

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Two children presented with a history of fever and rash. Lab values revealed pancytopenia, elevated ferritin, coagulopathy, and elevated triglycerides. Both children quickly developed respiratory distress and hypotension requiring admission to the ICU. Bone marrow biopsies revealed hemophagocytosis.

Efficacy and pharmacokinetics of the combination of etravirine plus raltegravir as novel dual antiretroviral maintenance regimen in HIV-infected patients.

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Novel combination antiretroviral regimens may be needed for selected HIV-infected patients with toxicity or resistance. We evaluated prospectively 25 virologically suppressed patients, largely pretreated (15.6 years on therapy) with antiretroviral drug toxicity (n=19) or interactions (n=9, mainly

A 48-week pilot study switching suppressed patients to darunavir/ritonavir and etravirine from enfuvirtide, protease inhibitor(s), and non-nucleoside reverse transcriptase inhibitor(s).

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Treatment options for HIV-infected patients can be limited due to viral drug resistance to antiretroviral agents. Enfuvirtide (ENF) is an injectable entry/fusion inhibitor that is effective in achieving viral suppression when used in combination with protease inhibitors (PIs) in patients with

Xanthoma-like Skin Changes in an Elderly Woman with a Normal Lipid Profile.

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Dear Editor, An 83-year-old woman developed yellow-brownish infiltrates, nodules, and tumors mimicking xanthomas, mostly involving the periorbital and chest area within three months (Figure 1). She had no abnormalities in serum cholesterol or triglycerides levels. A detailed laboratory analysis

Potential use of fenofibrate and other fibric acid derivatives in the clinic.

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The fibric acid derivatives continue to have a place in the treatment of hyperlipidemia. The third generation of these drugs, including fenofibrate, appears to offer some advantages over those currently available in the United States. These drugs should be prescribed only after dietary and lifestyle

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