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Anticancer and antibacterial secondary metabolites from the endophytic fungus Penicillium sp. CAM64 against multi-drug resistant Gram-negative bacteria.

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BACKGROUND The emergence of multiple-drug resistance bacteria has become a major threat and thus calls for an urgent need to search for new effective and safe anti-bacterial agents. OBJECTIVE This study aims to evaluate the anticancer and antibacterial activities of secondary metabolites from

Antibacterial xanthones from the leaves of Garcinia nigrolineata.

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Ten new 1,3,5-trioxygenated xanthones, nigrolineaxanthones J-S (1-10), one new quinone derivative, nigrolineaquinone A (11), and one new isoflavone-like compound, nigrolineaisoflavone A (12), were isolated from the leaves of Garcinia nigrolineata along with four known xanthones and friedelin. Among

Penialidins A-C with strong antibacterial activities from Penicillium sp., an endophytic fungus harboring leaves of Garcinia nobilis.

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Three new polyketides named penialidins A-C (1-3), along with one known compound, citromycetin (4), were isolated from an endophytic fungus, Penicillium sp., harbored in the leaves of the Cameroonian medicinal plant Garcinia nobilis. Their structures were elucidated by means of spectroscopic and

Endophytic fungi from tropical ethnoveterinary plants and their antibacterial efficacy against Pasteurella multocida Capsular Type A strain.

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Pasteurella multocida is an important veterinary pathogen causing infections in animals and birds. Nowadays, different reports have described the severity of infections, increasing resistance of micro-organisms to antibiotics, and the contribution of ethnoveterinary practices towards the treatment

In vitro antibacterial activity of mangosteen (Garcinia mangostana Linn.) crude extract against Staphylococcus pseudintermedius isolates from canine pyoderma.

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Staphylococcus pseudintermedius, commonly involved in canine pyoderma, can be classified as meticillin-susceptible S. pseudintermedius (MSSP) or meticillin-resistant S. pseudintermedius (MRSP). MRSP infections may be difficult to treat due to broad β-lactam resistance of MRSP and

Comparative ethnobotany and in-the-field antibacterial testing of medicinal plants used by the Bulu and inland Kaulong of Papua New Guinea.

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BACKGROUND The island of New Britain in Papua New Guinea is an area of great floristic and cultural diversity that has received little attention from ethnobotanists. Here we present the results of a comparative medicinal ethnobotanical survey of the Bulu and inland Kaulong; two distinct people

Antibacterial and brine shrimp lethality tests of biflavonoids and derivatives of Rheedia gardneriana.

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The hydroalcoholic extract of the leaves from Rheedia gardneriana yielded volkensiflavone (1), fukugetin (2), fukugiside (3), GB2a-I-7-O-glucoside (4) and epicatechin (5). Compounds 1-5, and some derivatives of 1 and 2 were evaluated for lethality to brine shrimp larvae and for antibacterial

Antibacterial activity of extracts from five medicinal plants and their formula against bacteria that cause chronic wound infection.

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BACKGROUND Chronic wound is caused by various factors such as chemotherapy, gene damage, treatment with steroids, diabetes mellitus, renal failure, blood pressure, infection and nutritional factors. One of the most common causes is bacterial infection. Antibacterial activity of several herbal plants

Complete NMR assignments of the antibacterial biflavonoid GB1 from Garcinia kola.

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From the antibacterial fraction of the roots of Garcinia kola, 3'',4',4''',5,5'',7,7''-heptahydroxy-3,8''-biflavanone (GB1) was isolated as the major constituent, whose interesting conformations were studied on the basis of its 1D and 2D NMR spectra obtained at different temperatures and in

Isolation and characterization of an antibacterial biflavonoid from an African chewing stick Garcinia kola Heckel (Clusiaceae).

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BACKGROUND The use of African chewing sticks in maintaining oral health is widely practiced in African countries. It has been reported that chewing stick users have a lower rate of dental caries and a better general oral health than non-users. It is generally thought that the beneficial effect of

An antibacterial biphenyl derivative from Garcinia bancana MIQ.

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From the methanol extract of the twigs and leaves of Garcinia bancana MIQ., one new biphenyl derivative (1), was isolated and characterized along with nine known compounds; garcinol, isogarcinol, (-)-mellein, 8-hydroxy-6-methoxy-3-n-pentylisocoumarin, blumenol C O-beta-D-glucoside, quercetin

Antibacterial dihydrobenzopyran and xanthone derivatives from Garcinia cowa stem barks.

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Two new compounds, garciniacowol (1) and garciniacowone (2) along with 15 knowncompounds were isolated from the stem barks of Garcinia cowa. Their structures weredetermined by intensive spectroscopic methods. The structure of 1 was a symmetrical dimericdihydrobenzopyran derivative, whereas the

Antibacterial and antioxidant xanthones and benzophenone from garcinia smeathmannii.

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A new prenylated xanthone, 1,3,5,8-tetrahydroxy-2-(3-methybut-2-enyl)-4-(3,7-dimethylocta-2,6-dienyl) xanthone (1), and a new benzophenone (2), together with four known xanthone derivatives, cheffouxanthone (3), smeathxanthone A (4), smeathxanthone B (5), ananixanthone (6), and two pentacyclic

A novel xanthone dimer derivative with antibacterial activity isolated from the bark of Garcinia mangostana.

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A novel xanthone dimer derivative, garmoxanthone (1), together with 10 known compounds (2-11), were isolated from bark of Garcinia mangostana. Their structures were established through spectroscopic methods. Garmoxanthone exhibited strong inhibitory activities against MRSA ATCC 43300 and MRSA CGMCC

Antibacterial activity of Garcinia mangostana extracts on oral pathogens.

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OBJECTIVE This study was conducted to evaluate the antibacterial activity of Garcinia mangostana (GM) extracts on oral pathogens. METHODS The 95% ethanol and 70% acetone extracts of the pericarp of GM was prepared and standardized by determining the amount of α-mangostin, total phenolic compounds

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