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glycosidase/φλεγμονή
Ο σύνδεσμος αποθηκεύεται στο πρόχειρο
Σελίδα 1 από 154 Αποτελέσματα
[Lysosomal glycosidases, lactate dehydrogenase and creatine phosphokinase in experimental inflammation].
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Σύνδεση εγγραφή
Inflammation of rat hypodermic tissue was accompanied by an increase in activity of lysosomal glycosidases beta-D-galactosidase and beta-D-glucuronidase in the proliferating tissue and in some other preparations studied. Activation of lactate dehydrogenase/LDH/in exudate of inflamed tissues
The Influence of Some Nonsteroidal Anti-inflammatory Drugs on Metabolic Enzymes of Aldose Reductase, Sorbitol Dehydrogenase, and α-Glycosidase: a Perspective for Metabolic Disorders.
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Σύνδεση εγγραφή
Pain, as a sensible alarm signal of living organisms to avoid tissue damage, is a common and debilitating consequence of a lot of disorders and diseases. The management of chronic pain is particularly challenging. For pain treatment, many analgesic drugs are used for their therapeutic effects. In
Profile of glycosaminoglycan-degrading glycosidases and glycoside sulfatases secreted by human articular chondrocytes in homeostasis and inflammation.
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Σύνδεση εγγραφή
OBJECTIVE
To determine enzymatic activities of the 8 key glycosaminoglycan-degrading glycosidases and glycoside sulfatases in cultured human articular chondrocytes and in synovial fluid from patients with osteoarthritis.
METHODS
The following enzymes were analyzed: hexosaminidase and its isoenzyme
Synergic effect of bacterial glycosidases and digestive proteases on mucus degradation and the reduced risk of inflammatory bowel disease-like gut damage in both germ-free and poor hygiene conditions.
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Σύνδεση εγγραφή
A defect in the inflammation-primed macrophage-activation cascade in osteopetrotic rats.
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Σύνδεση εγγραφή
Macrophages were activated by administration of lysophosphatidylcholine (lyso-Pc) or dodecylglycerol (DDG) to wild-type rats but not in osteopetrotic (op) mutant rats. In vitro treatment of wild-type rat peritoneal cells with lyso-Pc or DDG efficiently activated macrophages whereas treatment of op
Altered glycosylation of alpha1-acid glycoprotein in patients with inflammation and diabetes mellitus.
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Σύνδεση εγγραφή
BACKGROUND
In certain pathophysiological conditions, such as inflammation rheumatoid arthritis and diabetes mellitus (DM), alterations in asparagine-linked glycan (N-glycan) patterns of the acute-phase protein, alpha(1)-acid glycoprotein (AGP), have been reported. In this study, we investigated
The mutation Ser511Asn leads to N-glycosylation and increases the cleavage of high molecular weight kininogen in rats genetically susceptible to inflammation.
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Σύνδεση εγγραφή
Crohn disease is immunologically mediated and characterized by intestinal and systemic chronic inflammation. In a rat model, injection of peptidoglycan-polysaccharide complexes into the intestinal wall induced chronic inflammation in Lewis but neither Fischer nor Buffalo rats, indicating a
Glycosylation of site-specific glycans of alpha1-acid glycoprotein and alterations in acute and chronic inflammation.
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Σύνδεση εγγραφή
BACKGROUND
alpha(1)-Acid glycoprotein (AGP), an acute phase reactant, is extensively glycosylated at five Asn-linked glycosylation sites. In a number of pathophysiological states, including inflammation, rheumatoid arthritis, and cancer, alterations of Asn-linked glycans (N-glycans) have been
Gaultherin, a natural salicylate derivative from Gaultheria yunnanensis: towards a better non-steroidal anti-inflammatory drug.
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Σύνδεση εγγραφή
One of the major factors limiting the use of non-steroidal anti-inflammatory drugs is gastrointestinal toxicity. Gaultherin, 2-[(6-O-beta-D-Xylopyranosyl-beta-D-glucopyranosyl)oxy] benzoic acid methyl ester, a natural salicylate derivative extracted from Gaultheria yunnanensis, has been shown to
Rational design of a β-glycosidase with high regiospecificity for triterpenoid tailoring.
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Σύνδεση εγγραφή
Triterpenoids with desired glycosylation patterns have attracted considerable attention as potential therapeutics for inflammatory diseases and various types of cancer. Sugar-hydrolyzing enzymes with high substrate specificity would be far more efficient than other methods for the synthesis of such
Presence of the factor increasing monocytopoiesis (FIM) in rabbit peripheral blood during an acute inflammation.
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An intraperitoneal injection of latex in rabbits was found to give rise to an increase in the number of macrophages at the site of inflammation and a concomitant monocytosis in the peripheral blood. The results showed that during the initial phase of the inflammatory reaction a humoral factor is
Deglycosylation of alpha 1-proteinase inhibitor is impaired in the faeces of patients with active inflammatory bowel disease (Crohn's disease).
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Σύνδεση εγγραφή
1. alpha 1-Proteinase inhibitor (alpha 1-antitrypsin) was excreted in the faeces of patients with inflammatory bowel disease in different molecular forms: Mr-51,000 and Mr-45,000 forms were widely found in the stools of patients with active disease, whereas a Mr-38,000 species was frequently
Glycoprotein metabolism in inflammatory and neoplastic diseases of the human colon.
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Σύνδεση εγγραφή
Carbohydrate compositions of the membrane and cytoplasmic fractions of human normal and cancerous colonic mucosa were compared in patients with blood groups O and B. The total sugar content in both fractions was reduced in the cancer tissues to about one-third of that in the normal colonic mucosa.
On the mediation inflammatory reaction in the human gallbladder epithelium.
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Σύνδεση εγγραφή
Human gallbladder epithelium was homogenized with a view to maintaining the integrity of subcellular components. In such homogenates, N-acetyl-beta-glucosaminidase, beta-glucuronidase, beta-galactosidase, beta-glucosidase, beta-fucosidase, beta-xylosidase, and acid phosphatase were demonstrated
Glycoprotein biosynthesis during the acute-phase response to inflammation.
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Σύνδεση εγγραφή
Inflammation results in an increase in the levels of a variety of glycoproteins in serum. The glycoproteins that respond in this way are usually referred to as acute-phase reactants. Studies on the acute-phase response of rat alpha 1-acid glycoprotein showed that there was an increase in the liver
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