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hyperthyroidism/protease
Ο σύνδεσμος αποθηκεύεται στο πρόχειρο
14 Αποτελέσματα
Increased activity of intramuscular proteases in the hyperthyroid state.
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Σύνδεση εγγραφή
Early neuropsychological adverse events after switching from PI/r to dolutegravir could be related to hyperthyroidism in patients under levothyroxine.
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Σύνδεση εγγραφή
We report two patients who had taken levothyroxine at the same dose for several years and who had stable thyroid stimulating hormone (TSH) levels, and who developed clinical and biological hyperthyroidism following switch from ritonavir-boosted protease inhibitors (PIs) to dolutegravir-based HAART.
The effect of protease inhibition on the temporal stability of NT-proBNP in feline plasma at room temperature.
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Σύνδεση εγγραφή
OBJECTIVE
To evaluate whether the addition of a protease inhibitor (PI) to feline plasma improves the temporal stability of N-terminal pro-B-type natriuretic peptide (NT-proBNP).
METHODS
Forty-four EDTA blood samples were collected from 42 cats with cardiac disease or hyperthyroidism. Samples were
Gene expression profiles differ markedly in mouse strains that are (or are not) susceptible to hyperthyroidism induced using thyrotropin receptor-expressing adenovirus.
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Σύνδεση εγγραφή
BALB/c mice are susceptible and C57BL/6 mice are resistant to Graves' hyperthyroidism induced by immunization with adenovirus encoding the thyrotropin receptor (TSHR) A-subunit. Both strains develop comparable levels of TSHR antibodies, but potent TSH blocking antibody activity in C57BL/6 mice
Cathepsin S is not crucial to TSHR processing and presentation in a murine model of Graves' disease.
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Σύνδεση εγγραφή
By regulating invariant (Ii) chain processing and MHC class II peptide loading, the endosomal protease cathepsin S (Cat S) has a potential role in autoimmune susceptibility. Indeed, Cat S null mice are resistant to I-Ab-restricted experimental myasthenia gravis due to inadequate peptide
Elastase inhibitory activity in serum of patients with thyroid dysfunction.
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Σύνδεση εγγραφή
Dermal elastic fiber fragmentation and decreased fiber density are characteristic cutaneous abnormalities in myxedema. We therefore evaluated elastase inhibitory activity in serum in thyroid dysfunctional states by measuring the protease inhibitor alpha 1-antitrypsin (A-1-AT), as well as by directly
THE ABSENCE OF THYROID DISEASE IN AN AUSTRALIAN HEPATITIS C COHORT TREATED WITH TRIPLE COMBINATION THERAPY: A PARADIGM SHIFT.
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Σύνδεση εγγραφή
OBJECTIVE
To assess the prevalence of thyroid disease in triple combination therapy with interferon (IFN)-α, ribavirin (RBV), and protease inhibitors (boceprevir and telaprevir) for the treatment of chronic hepatitis C virus (HCV) infection in an Australian hepatitis C cohort. Also, to compare with
Possible participation of colloid antigen 2 and abhormone (IgG with hormone activity) for the etiology of Graves' disease.
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Σύνδεση εγγραφή
The theory that antibody (Ab) directed against the TSH receptor (TSHR) (TSHRAb) is the causal factor of Graves' disease seems unlikely. Corticosteroids have not had a curative effect on the hyperthyroidism of Graves' disease despite their effectiveness for other autoimmune diseases. Two kinds of
Thyroid screening in HIV-infected patients with antiretroviral therapy.
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Σύνδεση εγγραφή
BACKGROUND
The literature reports an increased incidence of thyroid disorders in human immunodeficiency virus (HIV)-positive persons. We therefore retrospectively analyzed the strategy of collecting thyroid parameters on a routine basis.
METHODS
Overall 410 patients (147 women, 263 men; age, 10-74
Micromethod of human thyrocyte cultures for detection of thyroid-stimulating antibodies and thyrotrophin.
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Σύνδεση εγγραφή
The activation of adenylate cyclase of human thyrocytes in primary cell cultures and the release of cAMP into the medium are used to detect thyrotropin (TSH) and thyroid-stimulating antibodies (TSAb) in sera of patients with Graves' disease. Tissue digestion and cell dispersion are performed using a
Interaction between levothyroxine and indinavir in a patient with HIV infection.
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Σύνδεση εγγραφή
Drug interactions are an important and emerging problem in the treatment of HIV-infected patients. Protease inhibitors, like nonnucleoside reverse transcriptase inhibitors, are metabolized by the cytochrome P-450 enzyme system and each of these antiretroviral agents may interact with other drugs
Molecular basis for the autoreactivity against thyroid stimulating hormone receptor.
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Σύνδεση εγγραφή
The present report identifies an important immunogenic region of the TSH receptor and determinants on the TSH receptor for the two types of autoantibodies seen in hyperthyroid Graves' disease and hypothyroid idiopathic myxedema, TSAbs and TSBAbs, respectively. The immunogenic domain with no
A high-molecular-weight cysteine endopeptidase from rat skeletal muscle.
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Σύνδεση εγγραφή
A cytosolic enzyme of high molecular weight (about 500 000), which attacks native or denatured proteins (inter alia, casein, globin and hexokinase) was purified about 1000-fold from mixed rat skeletal muscles, including muscles freed of mast cells by prior treatment of the animals with the
Thyroid function differently affects serum cystatin C and creatinine concentrations.
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Σύνδεση εγγραφή
Cystatin C (Cys C) is a cysteine protease inhibitor produced at a constant rate by nucleated cells, filtered through the glomerular membrane and reabsorbed by kidney tubular cells. Aim of this cross-sectional and longitudinal study was to assess serum Cys C and creatinine (Crea) concentrations in
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