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osteonecrosis/phosphatase
Ο σύνδεσμος αποθηκεύεται στο πρόχειρο
Σελίδα 1 από 219 Αποτελέσματα
Serum N-telopeptide and bone-specific alkaline phosphatase levels in patients with osteonecrosis of the jaw receiving bisphosphonates for bone metastases.
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Σύνδεση εγγραφή
OBJECTIVE
Oversuppression of bone turnover can be a critical factor in the pathogenesis of osteonecrosis of the jaw (ONJ). We investigated N-telopeptide of type I collagen (NTX) and bone-specific alkaline phosphatase (BAP) as potential predictors of ONJ onset.
METHODS
Patients with ONJ and available
Serum-alkaline-phosphatase as predictor of avascular necrosis of bone in renal-transplant recipients.
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Σύνδεση εγγραφή
MiR-181d promotes steroid-induced osteonecrosis of the femoral head by targeting SMAD3 to inhibit osteogenic differentiation of hBMSCs.
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Σύνδεση εγγραφή
OBJECTIVE
We aimed to investigate whether miR-181d may be involved in steroid-induced osteonecrosis of the femoral head (ONFH) and its underlying mechanism.
METHODS
Quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) was used to detect the expression of miR-181d in bone marrow of
Interferon β protects against avascular osteonecrosis through interleukin 6 inhibition and silent information regulator transcript-1 upregulation.
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Σύνδεση εγγραφή
Synovitis of the affected joint is a common in avascular osteonecrosis (AVN). Increased levels of pro-inflammatory cytokine interleukin-6 (IL-6) have been reported in AVN, but the mechanism of this increase remains unclear. Silent information regulator transcript-1 (SIRT1), an NAD-dependent
P-glycoprotein overexpression in bone marrow-derived multipotent stromal cells decreases the risk of steroid-induced osteonecrosis in the femoral head.
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Σύνδεση εγγραφή
P-glycoprotein (P-gp) plays a role in steroid-induced osteonecrosis of the femoral head (ONFH), but the underlying mechanism remains unknown. We hypothesized that P-gp overexpression can prevent ONFH by regulating bone marrow-derived multipotent stromal cell (BMSC) adipogenesis and osteogenesis.
Glucocorticoid inhibits bone regeneration after osteonecrosis of the femoral head in aged female rats.
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Σύνδεση εγγραφή
Idiopathic osteonecrosis of the femoral head (ION) is a painful disease of the hip, the pathogenic mechanism of which is still unclear. The most common extraneous factor is steroid treatment. Steroids have inhibiting effects on bone formation and resorption. When bone regenerative treatments are
Metformin coordinates osteoblast/osteoclast differentiation associated with ischemic osteonecrosis.
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Σύνδεση εγγραφή
In this study, we aimed to identify a candidate drug that can activate endogenous Angiopoietin 1 (Ang1) expression via drug repositioning as a pharmacological treatment for avascular osteonecrosis. After incubation with 821 drugs from the Food and Drug Administration (FDA)-approved drug library,
Prospective biomarker evaluation in patients with osteonecrosis of the jaw who received bisphosphonates.
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Σύνδεση εγγραφή
Bone biomarkers have been suggested for the risk assessment for osteonecrosis of the jaw, a serious complication associated with bisphosphonate (BP) use; however, no consensus has been reached. This study investigated the possible associations between bone biomarkers and the development of
Immune response associated with Toll-like receptor 4 signaling pathway leads to steroid-induced femoral head osteonecrosis.
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BACKGROUND
Femoral head osteonecrosis is frequently observed in patients treated with excessive corticosteroids. The objective of the current study was to establish a rat model to investigate the disruption of immune response in steroid-induced femoral head osteonecrosis via Toll-like receptor 4
Association of toll-like receptor 4 signaling pathway with steroid-induced femoral head osteonecrosis in rats.
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Σύνδεση εγγραφή
Osteonecrosis of the femoral head is frequently observed in patients treated with excessive corticosteroids. However, the pathogenesis of corticosteroid-induced osteonecrosis remains unclear. The purpose of this study was to investigate the role of Toll-like receptor 4 (TLR4) signaling pathway in
Isolation of prostaglandin E2-like material from osteonecrosis induced by steroids and its prevention by kallikrein-inhibitor, aprotinin. An experimental study in rabbits.
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Σύνδεση εγγραφή
Prostaglandin E2 (PGE2)-like activity was measured in osteonecrotic femoral heads caused by high doses of methyl prednisolone acetate in rabbits. Serum levels of cholesterol, total lipids, free fatty acids, alkaline phosphatase, SGOT and lipase were also determined. There were increases in local
Changes in serological bone turnover markers in bisphosphonate induced osteonecrosis of the jaws: A case control study.
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Σύνδεση εγγραφή
Spontaneous osteonecrosis of the knee: biochemical markers of bone turnover and pathohistology.
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Σύνδεση εγγραφή
OBJECTIVE
The aim of this study was to evaluate bone metabolism in patients with spontaneous osteonecrosis (ON) of the medial femoral condyle.
METHODS
In 22 consecutive patients, undergoing total knee arthroplasty, biochemical markers of bone metabolism were measured in aspirates from cancellous
Effects of metformin on the prevention of bisphosphonate-related osteonecrosis of the jaw-like lesions in rats
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Σύνδεση εγγραφή
Purpose: In this study, we aimed to investigate the effect of glucose metabolism on bone healing after tooth extraction in an osteoporosis rat model administered zoledronic acid (ZA) and dexamethasone (DX).
Aminobisphosphonate-treated ewes as a model of osteonecrosis of the jaw (ONJ) and of dental implant failure.
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Σύνδεση εγγραφή
METHODS
Eleven ovariectomized (OVX) ewes and 4 ewes subjected to sham surgery (SHAM) were treated asΗ πληρέστερη βάση δεδομένων φαρμακευτικών βοτάνων που υποστηρίζεται από την επιστήμη
- Λειτουργεί σε 55 γλώσσες
- Βοτανικές θεραπείες που υποστηρίζονται από την επιστήμη
- Αναγνώριση βοτάνων με εικόνα
- Διαδραστικός χάρτης GPS - ετικέτα βότανα στην τοποθεσία (σύντομα)
- Διαβάστε επιστημονικές δημοσιεύσεις που σχετίζονται με την αναζήτησή σας
- Αναζήτηση φαρμακευτικών βοτάνων με τα αποτελέσματά τους
- Οργανώστε τα ενδιαφέροντά σας και μείνετε ενημερωμένοι με την έρευνα ειδήσεων, τις κλινικές δοκιμές και τα διπλώματα ευρεσιτεχνίας
Πληκτρολογήστε ένα σύμπτωμα ή μια ασθένεια και διαβάστε για βότανα που μπορεί να βοηθήσουν, πληκτρολογήστε ένα βότανο και δείτε ασθένειες και συμπτώματα κατά των οποίων χρησιμοποιείται.
* Όλες οι πληροφορίες βασίζονται σε δημοσιευμένη επιστημονική έρευνα
