phytomenadione 10 mg (1 vial in the venous line of the extracorporeal hemodialysis circuit) post hemodialysis 3 times a week for 12 months

1 vial of placebo solution (solution for injection in the venous line of the extracorporeal hemodialysis circuit) post hemodialysis 3 times a week for 12 months

Coronary Calcification

phytomenadione

placebo solution

Hospital de Alta Especialidad No. 1 Bajío, Boulevard Adolfo López Mateos esquina Insurgentes S/N, colonia Los Paraísos

Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients

Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients. Randomized Clinical Trial

Within the population of hemodialysis patients, patients who met the inclusion criteria were sought, once the participation in the study was accepted and an informed consent was signed, a coronary tomography was performed and interpreted by Radiology staff, who had no knowledge about the study groups or their intervention. Those patients who fulfilled the coronary calcification tomographic criterion defined as coronary calcium score of 10 Agatston units were randomized to receive the intervention or the placebo. At the end of the 12 month follow-up, a coronary tomography was performed again to quantify the final Agatston score

determine presence of cardiovascular events like acute myocardial infarction, unstable angina and death of cardiac cause during follow-up. The presence of events will be determined according to the clinical record in the patient's file

Hilda Elizabeth Macias Cervantes

Doctor

Instituto Mexicano del Seguro Social

Marco Antonio Ocampo Apolonio

Rodolfo Guardado Mendoza

Texar Alfonso Pereyra Nobara

randomized clinical trial with double blinding compared to placebo

Patients were randomly assigned to receive intravenous vitamin K or placebo solution. Coronary tomography was performed and interpreted by Radiology staff, who had no knowledge about the study groups or their intervention

phytomenadione/έμφραγμα του μυοκαρδίου

Effects of Fhytomenadione on Coronary Artery Calcification of Hemodialysis Patients

Η πληρέστερη βάση δεδομένων φαρμακευτικών βοτάνων που υποστηρίζεται από την επιστήμη