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ribonucleic acid/hypoxia
Ο σύνδεσμος αποθηκεύεται στο πρόχειρο
Σελίδα 1 από 115 Αποτελέσματα
Relative quantitative expression of hypoxia-inducible factor 1α messenger ribonucleic acid in recurrent craniopharyngiomas.
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Σύνδεση εγγραφή
BACKGROUND
Craniopharyngioma is a benign tumor, but recurrences are common and prognosis is poor. The pathologic mechanism underlying the high recurrence is still unknown.
OBJECTIVE
We hypothesized that there are hypoxic microenvironments within craniopharyngiomas and hypoxia inducible factor-1
Anti-angiogenic effects of ribonucleic acid interference targeting vascular endothelial growth factor and hypoxia-inducible factor-1alpha.
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OBJECTIVE
To compare the in vitro anti-angiogenic effects of inhibiting vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1-alpha (HIF-1alpha) using ribonucleic acid (RNA) interference (RNAi).
METHODS
Laboratory investigation.
METHODS
VEGF or HIF-1alpha was antagonized in human
Effect of gestational age and hypoxia on activity of ribonucleic acid polymerase in fetal guinea pig brain.
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Σύνδεση εγγραφή
OBJECTIVE
The aim of this study was to determine the effect of gestational age and hypoxia on the activity of ribonucleic acid polymerase in fetal guinea pig brain.
METHODS
Fetal cerebral cortical neuronal nuclei were isolated at 40, 50, and 60 days (term) of gestation to determine the effect of
Differential regulation of proopiomelanocortin messenger ribonucleic acid in the pars distalis and pars intermedia of the pituitary gland after prolonged hypoxemia in fetal sheep.
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Σύνδεση εγγραφή
POMC messenger RNA (mRNA) is synthesized and translated to form ACTH in the pars distalis and ACTH-related peptides in the pars intermedia of the pituitary in fetuses of species such as sheep. In the fetal sheep, maturation of hypothalamo-pituitary-adrenal (HPA) function occurs during late pregnancy
Safflor yellow B reduces hypoxia-mediated vasoconstriction by regulating endothelial micro ribonucleic acid/nitric oxide synthase signaling.
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Σύνδεση εγγραφή
Hypoxia-induced generation of vasoconstrictors reduces cerebral blood flow (CBF) while nitric oxide (NO) synthase (NOS) and microRNAs (miRNA) in endothelial cells (ECs) suppress vasoconstriction. Safflor yellow B (SYB), a natural plant compound, previously attenuated angiotensin II-mediated injury
Adaptation of ribonucleic Acid metabolism to anoxia in rice embryos.
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Σύνδεση εγγραφή
Rice (Oryza sativa var. Cigalon) is a plant which can adapt to very stringent anoxic conditions. It has previously been shown that during the adaptation period the energy charge can be used as a marker for metabolic activity. We have studied RNA metabolism during this period and correlated it with
The effect of hypoxia from birth on the regulation of aldosterone in the 7-day-old rat: plasma hormones, steroidogenesis in vitro, and steroidogenic enzyme messenger ribonucleic acid.
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Σύνδεση εγγραφή
Adaptation to hypoxia in the neonate requires an appropriate adrenocortical response. The purpose of this study was to examine the adaptation of the aldosterone pathway in rat pups exposed to hypoxia in vivo from birth to 7 days of age. Neonatal rats (with their lactating dams) were exposed to
[The state of ribonucleic acids and respiratory enzymes in sympathetic neurons during hypoxia].
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ANP gene expression in rat hearts during hypoxia.
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Σύνδεση εγγραφή
It is unclear whether the increase in plasma atrial natriuretic peptide (ANP) concentration during hypoxia is due to direct, hypoxia-induced upregulation of ANP secretion in the heart, or to pressure overload of the right ventricle (RV) following hypoxia-induced pulmonary hypertension. To test the
Pum2 Mediates Sirt1 mRNA Decay and Exacerbates hypoxia/reoxygenation-induced Cardiomyocyte Apoptosis
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Σύνδεση εγγραφή
Pum2 is a ribonucleic acid binding protein that controls target mRNA turnover. It has been reported to be potentially associated with cardiac fibrosis. However, little is known about the role of Pum2 in cardiac disease. In this study, we found that Pum2 was upregulated in the rat heart tissue
Chemokine response of pulmonary artery endothelial cells to hypoxia and reoxygenation.
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BACKGROUND
Chemokines are inflammatory mediators that activate and recruit specific leukocyte subpopulations. We have recently shown a role for certain chemokines in a warm in situ rat model of lung ischemia reperfusion injury. After hypoxic stress, rat pulmonary artery endothelial cells (RPAECS)
Effects of hypoxia inducible factor-1alpha (HIF-1alpha) on the growth & adhesion in tongue squamous cell carcinoma cells.
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OBJECTIVE
Hypoxia-inducible factor-1 alpha (HIF-1alpha) is a central transcriptional regulator of hypoxic response. Suppression of HIF-1alpha is important for exploring hypoxia-induced pathophysiological events. This study was carried out to analyze the hypoxia-induced changes of biological
Expression of hypoxia-inducible factor-1alpha in esophageal squamous cell carcinoma.
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Σύνδεση εγγραφή
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that plays an important role in tumor growth and metastasis by regulating energy metabolism and inducing angiogenesis. Elevated levels of HIF-1alpha, a subunit of HIF-1, are noted in various malignant tumors, but it is unclear whether this
Hypoxia increases insulinlike growth factor gene expression in rat osteoblasts.
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Σύνδεση εγγραφή
Vascular disruption secondary to fracture leads to a hypoxic zone of injury where the oxygen tension at the center of the wound is quite low. In this dynamic microenvironment, a number of growth factors are elaborated to stimulate the synthetic processes of fracture repair. Previously the authors
Long noncoding RNA-regulator of reprogramming alleviates hypoxia-induced cerebral injury in mice model and human via modulating apoptosis complexes.
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Σύνδεση εγγραφή
Ischemic stroke causes cerebral hypoxia, while long non-coding RNA regulator of reprogramming is associated with hypoxia. To find a new intervention target to protect hypoxic cerebral tissue and a potential biomarker from reflecting the severity of hypoxia after ischemic stroke, our research
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