Using Gum Arabic for Cancer Patients to Protect From Oral Mucositis Caused by Chemotherapy: ِِِAn Experimental Study
Keywords
Abstract
Dates
Last Verified: | 10/31/2017 |
First Submitted: | 10/31/2017 |
Estimated Enrollment Submitted: | 11/16/2017 |
First Posted: | 11/19/2017 |
Last Update Submitted: | 11/16/2017 |
Last Update Posted: | 11/19/2017 |
Actual Study Start Date: | 10/25/2015 |
Estimated Primary Completion Date: | 07/31/2016 |
Estimated Study Completion Date: | 07/31/2016 |
Condition or disease
Intervention/treatment
Drug: Gum Arabic group
Drug: Chemotherapy
Behavioral: Lifestyle counseling
Phase
Arm Groups
Arm | Intervention/treatment |
---|---|
Experimental: Gum Arabic group Patients of study group was received a dose of 30 grams Gum Arabic per day as oral solution (dissolved in 250 ml purified water) for six weeks along with the chemotherapy prescribed addition to verbal instructions pertaining to the optimal nutrition and daily routine for oral hygiene. | Drug: Gum Arabic group Gum acacia, also known as Gum Arabic is exuded from acacia trees; mainly from Acacia Senegal (gum Hashab or Kordofan gum) which was used in this study. |
Other: Control group Patients of control group was received only chemotherapy regimen and verbal counseling pertaining to the optimal nutrition and daily routine for oral hygiene. |
Eligibility Criteria
Ages Eligible for Study | 14 Years To 14 Years |
Sexes Eligible for Study | All |
Accepts Healthy Volunteers | Yes |
Criteria | Inclusion Criteria: - Patients whom well diagnosed with cancer in any stage were eligible for enrolment if chemotherapy is part of their treatment plan. Exclusion Criteria: Patients were excluded if - they had received recent previous chemotherapy or radiotherapy, - they had oral mucositis or periodontitis, - there is evidence of any systemic diseases. |
Outcome
Primary Outcome Measures
1. The effect of Gum Arabic to prevent Chemotherapy-induced Oral Mucositis was the primary outcome that assessed using World Health Organization Mucositis Scoring. [Six weeks for each participant from starting therapy.]