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Natural Product Communications 2016-May

A New Alkenylmethylresorcinol from the Fruits of Ardisia kivuensis.

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Yves M M Nguekeu
Blanche L Ndontsa
Roukayatou Mbouangouere
Maurice D Awouafack
Takuya Ito
Pierre Tane
Hiroyuki Morita

Keywords

Abstract

The phytochemical study of the MeOH extract from the fruits of Ardisia kivuensis was carried out using repeated silica gel column chromatography followed by Sephadex LH-20 to afford a new alkenylmethylresorcinol, ardisinol III (1) along with three known compounds, oleanolic acid, β-sitosterol and pentacosanoic acid. The structure of 1 was elucidated using spectroscopic analysis (NMR and MS), and comparison with published data. Compound 1 had weak antioxidant activity (IC50 109.8 μg/mL) while other compounds were not active as compared to L-ascorbic acid (IC50 3.9 μg/mL).

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