Natural Product Communications 2016-Jan
A New Cytotoxic Clerodane Diterpene from Casearia graveolens Twigs.
Only registered users can translate articles
Log In/Sign up
The link is saved to the clipboard
Keywords
Abstract
The first phytochemical investigation of Casearia graveolens twigs led to the isolation and identification of a new clerodane diterpene, caseariagraveolin (1), together with six known compounds (2-7). Their structures were elucidated by intensive analysis of their spectroscopic data. Compound 1 showed strong cytotoxicity against oral cavity and breast cancer cell lines with IC₅₀ values of 2.48 and 6.63 µM, respectively.