Planta Medica 1999-Apr
A new antiviral and antimicrobial sesquiterpene from Glyptopetalum sclerocarpum.
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Keywords
Abstract
Sclerocarpic acid, a new sesquiterpene with a novel carbon skeleton, was isolated from the stem bark of Glyptopetalum sclerocarpum Laws. (Celastraceae). The compound exhibited antiviral activity against herpes simplex virus types 1 and 2, and antimicrobial activity against Gram-positive bacteria and a fungus.