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Carbohydrate Research 2008-Jan

A new kaempferol triglycoside from Fagonia taeckholmiana: cytotoxic activity of its extracts.

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Lamyaa F Ibrahim
Salwa A Kawashty
Ali M El-Hagrassy
Mahmoud I Nassar
Tom J Mabry

Keywords

Abstract

In addition to apigenin, apigenin 7-O-glucoside, kaempferol 3-O-glucoside, kaempferol 3,7-di-O-rhamnoside, quercetin, and quercetin 3-O-glucoside, the methanolic extract of Fagonia taeckholmiana afforded a new compound identified as kaempferol 3-O-beta-l-arabinopyranosyl-(1-->4)-alpha-l-rhamnopyranoside-7-O-alpha-l-rhamnopyranoside. Identification of the isolated compounds was based on chemical and spectroscopic analyses including UV, FABMS, (1)H, (13)C and 2D NMR, and DEPT. The cytotoxic activities of the compounds against several cancer cell lines were determined.

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