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Phytotherapy Research 2002-Aug

Aloe arborescens extract inhibits TPA-induced ear oedema, putrescine increase and tumour promotion in mouse skin.

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Kan Shimpo
Chikako Ida
Takeshi Chihara
Hidehiko Beppu
Takaaki Kaneko
Hiroshi Kuzuya

Keywords

Abstract

The ethyl acetate extract of the acetone-soluble Aloe arborescens fraction was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced ear oedema, putrescine increase and tumour promotion in mouse skin. Chromatographic analyses of this extract revealed that phenolic compounds such as aloenin, barbaloin and isobarbaloin could be useful as cancer chemopreventive agents against tumour promotion.

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