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Japanese Journal of Cancer and Chemotherapy 1991-Jul

[Alprazolam for patients with psychotic symptoms or autonomic imbalance symptoms after breast cancer surgery].

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K Tamaki
M Nishida
H Hiraide
S Tamakuma

Keywords

Abstract

Effectiveness of alprazolam in daily dosages of 0.8-1.2 mg was studied in 28 patients who showed psychotic symptoms or autonomic imbalance symptoms after operation for breast cancer. Psychotic symptoms included depression, anxiety, tension, and restlessness, and symptoms of autonomic imbalance included sleep disorder, anorexia, and pains. All of these symptoms were improved at high ratios by alprazolam. The drug was very useful in 16 cases (57.1%), useful in 11 cases (39.3%), and slightly useful in one case (3.6%). The only adverse reaction reported was unsteady gait in one case.

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