Journal of Pediatrics 1977-Mar
Aminophylline bioavailability and the across-time stability of plasma theophylline levels.
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Abstract
Three generic aminophylline products were examined and found to have equivalent bioavailability. Plasma theophylline levels were found to be reproducible in most patients (intraclass r = 0.7). There were some patients who showed wide swings in plasma theophylline levels without signs of toxicity or clinical deterioration.