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Bioorganic and Medicinal Chemistry Letters 2005-Oct

An antitumor compound julibroside J28 from Albizia julibrissin.

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Hong Liang
Wen-yong Tong
Yu-ying Zhao
Jing-rong Cui
Guang-zhong Tu

Keywords

Abstract

A new triterpenoid saponin, julibroside J(28) (1), was isolated from the stem bark of Albizia julibrissin Durazz (Leguminosae) by using chromatographic method. The structure of 1 was established by spectroscopic methods. 1 displayed significant antitumor activity in vitro against PC-3M-1E8, Bel-7402, and HeLa cancer cell lines at 10 microM assayed by SRB method.

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