Planta Medica 2000-Apr
Anti-inflammatory activity of coumarins from Decatropis bicolor on TPA ear mice model.
Only registered users can translate articles
Log In/Sign up
The link is saved to the clipboard
Keywords
Abstract
From the aerial parts of Decatropis bicolor, heraclenin (1), seselin (2), psoralen (3), imperatorin (4), skimmianine (5), and heraclenol (6), were isolated. This is the first time that coumarin-like compounds are isolated from Decatropis genus. The anti-inflammatory properties of compounds 1-6 were examined against the ear edema in mice produced by TPA. The results suggest that the anti-inflammatory activity of each compound depends of its individual substitution on the aromatic ring rather than the coumarin skeleton itself.