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Avicenna journal of phytomedicine 2012

Antibacterial activity of Glycyrrhiza glabra against oral pathogens: an in vitro study.

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Fereshteh Sedighinia
Akbar Safipour Afshar
Saman Soleimanpour
Reza Zarif
Javad Asili
Kiarash Ghazvini

Keywords

Abstract

OBJECTIVE

Oral infections and dental caries are still considered as serious public health problems and inflict a costly burden to health care services around the world and especially in developing countries.

METHODS

In the present study, we evaluated the antibacterial activity of Glycyrrhiza glabra (G. glabra) against oral pathogens by diffusion methods and determined the minimum inhibitory concentration (MIC) by both broth and Agar dilution methods and minimum bactericidal concentration (MBC) by broth dilution methods.

RESULTS

In this study, G. glabra extract showed good antibacterial activity against six bacteria. No strain in this study showed resistance against this extract.

CONCLUSIONS

G. glabrais suggested as an appropriate candidate to help us in order to control dental caries and endodontic infections.

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